@article{967e659b3c66423197b279eaae5fe4c9,
title = "Acetylation regulates WRN catalytic activities and affects base excision DNA repair",
abstract = "The Werner protein (WRN), defective in the premature aging disorder Werner syndrome, participates in a number of DNA metabolic processes, and we have been interested in the possible regulation of its function in DNA repair by post-translational modifications. Acetylation mediated by histone acetyltransferases is of key interest because of its potential importance in aging, DNA repair and transcription.",
keywords = "Aging, Catalysis, Cell Line, DNA, DNA Damage, DNA Repair, Exodeoxyribonucleases, Exonucleases, Hela Cells, Histone Acetyltransferases, Humans, Protein Processing, Post-Translational, Protein Structure, Tertiary, RecQ Helicases, Recombinant Proteins, Transcription, Genetic",
author = "Meltem Muftuoglu and Rika Kusumoto and Elzbieta Speina and Gad Beck and Wen-Hsing Cheng and Bohr, {Vilhelm A}",
year = "2008",
month = jan,
doi = "10.1371/journal.pone.0001918",
language = "English",
volume = "3",
pages = "e1918",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",
}