Nicolai Jacob Wewer Albrechtsen

Publikation

Publikationer pr. år 2013 2016 2017 2018 2019 2019

• 65 Tidsskriftartikel
• 6 Review
• 2 Konferenceabstrakt i tidsskrift
• 1 Encyclopædiartikel
• 3 Mere
  • 1 Kommentar/debat
  • 1 Konferenceartikel
  • 1 Udgivelser på nettet - Net-publikation

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

  Christiansen, C. B., Trammell, S. A. J., Albrechtsen, N. J. W., Schoonjans, K., Albrechtsen, R., Gillum, M. P., Kuhre, R. E. & Holst, J. J., maj 2019, I: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, s. G574-G584 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Peptide YY 100%
  • Glucagon-Like Peptide 1 82%
  • Bile Acids and Salts 73%
  • Rodentia 58%
  • Colon 33%
  15 Citationer (Scopus)

  1 Downloads (Pure)

• Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized Single-Blinded Placebo Controlled Study

  Behary, P., Tharakan, G., Alexiadou, K., Johnson, N., Albrechtsen, N. J. W., Kenkre, J., Cuenco, J., Hope, D., Anyiam, O., Choudhury, S., Alessimii, H., Poddar, A., Minnion, J., Doyle, C., Frost, G., Le Roux, C., Purkayastha, S., Moorthy, K., Dhillo, W., Holst, J. J., & 4 flereAhmed, A. R., Prevost, A. T., Bloom, S. R. & Tan, T. M., 1 aug. 2019, I: Diabetes Care. 42, 7, 8 s., dc190449.

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  • Oxyntomodulin 100%
  • Peptide YY 82%
  • Prediabetic State 74%
  • Glucagon-Like Peptide 1 67%
  • Gastric Bypass 47%
  29 Citationer (Scopus)

• Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study

  Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, N. J. W., Deacon, C. F., Parameshwar, J. & Hoole, S. P., jan. 2019, I: Clinical Therapeutics. 41, 1, s. 118-127 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon-Like Peptide 1 100%
  • Hemodynamics 62%
  • Heart Failure 62%
  • Lung 45%
  • Thermodilution 33%
  1 Citationer (Scopus)

• Effects of Exercise Training and IL-6 Receptor Blockade on Gastric Emptying and GLP-1 Secretion in Obese Humans: Secondary Analyses From a Double Blind Randomized Clinical Trial

  Lehrskov, L. L., Christensen, R. H., Wedell-Neergaard, A-S., Legaard, G. E., Dorph, E., Larsen, M. K., Henneberg, M., Launbo, N., Fagerlind, S. R., Seide, S. K., Nymand, S., Ball, M., Vinum, N., Dahl, C., Albrechtsen, N. J. W., Holst, J. J., Ried-Larsen, M., Rosenmeier, J. B., Krogh-Madsen, R., Karstoft, K., & 2 flerePedersen, B. K. & Ellingsgaard, H., 4 okt. 2019, I: Frontiers in Physiology. 10, 11 s., 1249 .

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Interleukin-6 Receptors 100%
  • Glucagon-Like Peptide 1 89%
  • Gastric Emptying 87%
  • Randomized Controlled Trials 51%
  • Exercise 49%
  3 Citationer (Scopus)

  3 Downloads (Pure)

• FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism

  Sakaguchi, M., Cai, W., Wang, C-H., Cederquist, C. T., Damasio, M., Homan, E. P., Batista, T., Ramirez, A. K., Gupta, M. K., Steger, M., Wewer Albrechtsen, N. J., Singh, S. K., Araki, E., Mann, M., Enerbäck, S. & Kahn, C. R., 1 dec. 2019, I: Nature Communications. 10, 1, 17 s., 1582.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • insulin 100%
  • metabolism 86%
  • Insulin Derivative 71%
  • Pharmacological Metabolism 54%
  • cytoplasm 51%
  14 Citationer (Scopus)

  15 Downloads (Pure)

• Glucagon Receptor Signaling and Glucagon Resistance

  Janah, L., Kjeldsen, S., Galsgaard, K. D., Winther-Sorensen, M., Stojanovska, E., Pedersen, J., Knop, F. K., Holst, J. J. & Albrechtsen, N. J. W., 1 jul. 2019, I: International Journal of Molecular Sciences. 20, 13, 27 s., 3314.

  Publikation: Bidrag til tidsskrift › Review › peer review

  26 Citationer (Scopus)

  8 Downloads (Pure)

• Glucagon Receptor Signaling and Lipid Metabolism

  Galsgaard, K. D., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., 2019, I: Frontiers in Physiology. 10, 11 s., 413.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon Receptors 100%
  • Glucagon 66%
  • Lipid Metabolism 61%
  • Liver 33%
  • Glucagon-Secreting Cells 14%
  23 Citationer (Scopus)

  31 Downloads (Pure)

• Glucose and Amino Acid Metabolism in Mice Depend Mutually on Glucagon and Insulin Receptor Signaling

  Galsgaard, K. D., Winther-Sørensen, M., Pedersen, J., Kjeldsen, S. A. S., Rosenkilde, M. M., Wewer Albrechtsen, N. J. & Holst, J. J., 2019, I: American Journal of Physiology: Endocrinology and Metabolism. 316, 4, s. E660-E673

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon Receptors 100%
  • Insulin Antagonists 92%
  • Insulin Receptor 72%
  • Amino Acids 44%
  • Glucose 40%
  11 Citationer (Scopus)

• Gut-derived glucagon in man: [Meeting Abstract]

  Baekdal, M., Lund, A., Albrechtsen, N. J. W., Egholk, J., Jorsal, T., Black-Juel, C. T., Hunt, J., Galsgaard, K. D., Rigbolt, K., Palnaes, C., Orskov, C., Poulsen, S. S., Holst, J. J., Villsboll, T. & Knop, F. K., 2019, I: Diabetologia. 62, Supl. 1/SI, s. S231-S231 472.

  Publikation: Bidrag til tidsskrift › Konferenceartikel › Forskning

• Identification of ADAM12 as a Novel Basigin Sheddase

  Albrechtsen, R., Wewer Albrechtsen, N. J., Gnosa, S., Schwarz, J., Dyrskjøt, L. & Kveiborg, M., 2 apr. 2019, I: International Journal of Molecular Sciences . 20, 8, 14 s., 1957 .

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Basigin 100%
  • Cells 61%
  • Metalloproteases 60%
  • cancer 59%
  • Conditioned Culture Medium 47%
  7 Citationer (Scopus)

  24 Downloads (Pure)

• Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

  Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N., & 3 flereJelsing, J., Vilsbøll, T. & Knop, F. K., 1 dec. 2019, I: Journal of Clinical Endocrinology and Metabolism. 104, 12, s. 6403–6416 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon 100%
  • Gastric Bypass 85%
  • Small Intestine 36%
  • Glucagon-Like Peptide 1 35%
  • Plasma Concentration 25%
  16 Citationer (Scopus)

• Methods and Guidelines for Measurement of Glucagon in Plasma

  Holst, J. J. & Albrechtsen, N. J. W., 1 nov. 2019, I: International Journal of Molecular Sciences (Online). 20, 10 s., 5416.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Glucagon 100%
  • Peptides 97%
  • Secretin 86%
  • peptides 81%
  • metabolic diseases 75%
  11 Citationer (Scopus)

  4 Downloads (Pure)

• Neuromedin U Does Not Act as a Decretin in Rats

  Kuhre, R. E., Christiansen, C. B., Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, I. M., Mandrup-Poulsen, T., Albrechtsen, R., Rosenkilde, M. M., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 2019, I: Cell Metabolism. 29, 3, s. 719-726.e1-e5 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • neuromedin U 100%
  • Insulin Secretion 24%
  • Hormones 23%
  • Pancreas 21%
  • Glucagon-Like Peptide 1 19%
  5 Citationer (Scopus)

  15 Downloads (Pure)

• No direct effect of SGLT2 activity on glucagon secretion

  Kuhre, R. E., Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, N. J. W., Andersen, D. B., Aivazidis, A., Chen, L., Mandrup-Poulsen, T., Ørskov, C., Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, J. J., 1 jun. 2019, I: Diabetologia. 62, 6, s. 1011-1023

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  • Glucagon 100%
  • Sodium-Glucose Transporter 2 55%
  • Somatostatin-Secreting Cells 41%
  • Glucose 40%
  • Methylglucosides 33%
  40 Citationer (Scopus)

• Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

  Jepsen, S. L., Grunddal, K. V., Wewer Albrechtsen, N. J., Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, C., Poulsen, S. S., Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, C. F., Schwartz, T. W., Christ, A. D., Martin, R. E. & Holst, J. J., dec. 2019, I: A J P: Endocrinology and Metabolism (Online).

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  • Enteroendocrine Cells 100%
  • Somatostatin-Secreting Cells 91%
  • Glucagon-Like Peptide 1 82%
  • Somatostatin 36%
  • somatostatin receptor 2 10%
  12 Citationer (Scopus)

• Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

  Mulla, C. M., Goldfine, A. B., Dreyfuss, J. M., Houten, S., Pan, H., Pober, D. M., Albrechtsen, N. J. W., Svane, M. S., Schmidt, J. B., Holst, J. J., Craig, C. M., McLaughlin, T. L. & Patti, M-E., 15 jul. 2019, I: Obesity Surgery. 29, 7, s. 2092-2099

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Bariatrics 100%
  • Fibroblast Growth Factors 95%
  • Hypoglycemia 76%
  • Gastric Bypass 49%
  • Glucagon-Like Peptide 1 33%
  9 Citationer (Scopus)

• Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

  Niu, L., Geyer, P. E., Albrechtsen, N. J. W., Gluud, L. L., Santos, A., Doll, S., Treit, P. V., Holst, J. J., Knop, F. K., Vilsbøll, T., Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, M., mar. 2019, I: Molecular Systems Biology. 15, 16 s., e8793.

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  • Profiling 100%
  • Liver 95%
  • fatty liver 87%
  • Polymeric Immunoglobulin Receptors 85%
  • Plasma 76%
  55 Citationer (Scopus)

  35 Downloads (Pure)

• Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men

  Wewer Albrechtsen, N. J., Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, B., Carr, R. D., Gustafsson, F., Deacon, C. F., Holst, J. J., Goetze, J. P. & Plomgaard, P., 1 sep. 2019, I: Journal of Clinical Endocrinology and Metabolism. 104, 9, s. 3868-3876

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Sacubitril 100%
  • Sitagliptin 82%
  • LCZ 696 81%
  • Glucagon-Like Peptide 1 79%
  • Valsartan 76%

• The liver-alpha cell axis and type 2 diabetes

  Wewer Albrechtsen, N. J., Pedersen, J., Galsgaard, K. D., Winther-Sørensen, M., Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, F. K. & Holst, J. J., 2019, I: Endocrine Reviews. 40, 5, s. 1353-1366

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Glucagon 100%
  • Type 2 Diabetes Mellitus 86%
  • Hyperinsulinism 63%
  • Liver 59%
  • Amino Acids 53%
  26 Citationer (Scopus)
• 2018

  Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

  Christiansen, C. B., Lind, S. J., Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, R. E., Hartmann, B., Mandrup-Poulsen, T., Deacon, C. F., Albrechtsen, N. J. W. & Holst, J. J., jul. 2018, I: Physiological Reports. 6, 13, s. 1-8 e13788.

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  • Glucagon-Like Peptide 1 100%
  • Interleukin-6 65%
  • Glucagon 38%
  • Insulin Secretion 36%
  • Glucose 30%
  2 Citationer (Scopus)

  46 Downloads (Pure)

• ADAM12-mediated shedding of basigin controls the subcellular localization and lactate transport of MCT4 and enhances collagen degradation in cancer cells: [Meeting Abstract}

  Albrechtsen, R., Albrechtsen, N. J. W. & Kveiborg, M., 2018, I: International Journal of Experimental Pathology. 99, 6, s. A25-A25

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

• Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

  Kuhre, R. E., Albrechtsen, N. J. W., Larsen, O., Jepsen, S. L., Balk-Møller, E., Andersen, D. B., Deacon, C. F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, R., Hartmann, B., Rosenkilde, M. & Holst, J. J., 2018, I: Molecular Metabolism. 11, s. 84-95 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ghrelin 100%
  • Bile Acids and Salts 87%
  • Pancreas 71%
  • GTP-Binding Proteins 47%
  • Glucagon-Like Peptide 1 42%
  60 Citationer (Scopus)

  60 Downloads (Pure)

• Commentary: measurement of biomarkers in medicine

  Goetze, J. P., Hansen, L. H., Terzic, D., Mark, P. D., Wewer Albrechtsen, N. J., Plomgaard, P. & Rehfeld, J. F., sep. 2018, I: Biomarkers in Medicine. 12, 9, s. 941-944 4 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

• Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

  Galsgaard, K. D., Winther-Sørensen, M., Ørskov, C., Kissow, H., Poulsen, S. S., Vilstrup, H., Prehn, C., Adamski, J., Jepsen, S. L., Hartmann, B., Hunt, J., Charron, M. J., Pedersen, J., Albrechtsen, N. J. W. & Holst, J. J., jan. 2018, I: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, s. E93-E103

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon Receptors 100%
  • Glucagon 66%
  • Amino Acids 44%
  • Liver 33%
  • Glucagon-Secreting Cells 32%
  37 Citationer (Scopus)

• Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

  Wewer Albrechtsen, N. J., Færch, K., Jensen, T. M., Witte, D. R., Pedersen, J., Mahendran, Y., Jonsson, A. E., Galsgaard, K. D., Winther-Sørensen, M., Torekov, S. S., Lauritzen, T., Pedersen, O., Knop, F. K., Hansen, T., Jørgensen, M. E., Vistisen, D. & Holst, J. J., 1 mar. 2018, I: Diabetologia. 61, 3, s. 671-680

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  • Glucagon 100%
  • Insulin Resistance 78%
  • Fasting 76%
  • Amino Acids 67%
  • Liver 49%
  27 Citationer (Scopus)

• GLP-1 Is a Coronary Artery Vasodilator in Humans

  Clarke, S. J., Giblett, J. P., Yang, L. L., Hubsch, A., Zhao, T., Aetesam-ur-Rahman, M., West, N. E. J., O'Sullivan, M., Figg, N., Bennett, M., Albrechtsen, N. J. W., Deacon, C. F., Cheriyan, J. & Hoole, S. P., 1 nov. 2018, I: Journal of the American Heart Association. 7, 22, 14 s., e010321.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon-Like Peptide 1 100%
  • Vasodilator Agents 86%
  • Coronary Vessels 69%
  • Peptides 54%
  • Forearm 32%
  6 Citationer (Scopus)

  43 Downloads (Pure)

• Glucagon receptor signaling in metabolic diseases

  Albrechtsen, N. J. W., feb. 2018, I: Peptides. 100, s. 42-47

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  • Glucagon Receptors 100%
  • Glucagon 86%
  • Metabolic Diseases 67%
  • Metabolic 52%
  • Glucagon-Secreting Cells 24%
  11 Citationer (Scopus)

• Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes

  Wewer Albrechtsen, N. J., Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, K. D., Holst, J. J., Knop, F. K. & Vilsbøll, T., jan. 2018, I: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, s. G91-G96

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  • Glucagon 100%
  • Liver Diseases 98%
  • Type 2 Diabetes Mellitus 88%
  • Amino Acids 82%
  • Non-alcoholic Fatty Liver Disease 80%
  22 Citationer (Scopus)

• Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

  Petersen, N., Frimurer, T. M., Pedersen, M. T., Egerod, K. L., Wewer, A. N. J., Holst, J. J., Grapin-Botton, A., Jensen, K. B. & Schwartz, T. W., 2018, I: Gastroenterology. 155, 4, s. 1164-1176 4 s.

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  • Y 27632 100%
  • Glucagon-Like Peptide 1 99%
  • L Cells 79%
  • Intestines 76%
  • Enteroendocrine Cells 69%
  16 Citationer (Scopus)

• Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control

  Lehrskov, L. L., Lyngbaek, M. P., Soederlund, L., Legaard, G. E., Ehses, J. A., Heywood, S. E., Albrechtsen, N. J. W., Holst, J. J., Karstoft, K., Pedersen, B. K. & Ellingsgaard, H., 5 jun. 2018, I: Cell Metabolism. 27, 6, s. 1201-1211

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  • Gastric Emptying 100%
  • Interleukin-6 67%
  • Glucagon-Like Peptide 1 34%
  • Insulin Secretion 28%
  • Type 2 Diabetes Mellitus 21%
  38 Citationer (Scopus)

• Oxyntomodulin: actions and role in diabetes

  Holst, J. J., Albrechtsen, N. J. W., Gabe, M. B. N. & Rosenkilde, M. M., 2018, I: Peptides. 100, s. 48-53 6 s.

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  • Oxyntomodulin 100%
  • Glucagon 70%
  • Proprotein Convertase 1 58%
  • Proglucagon 55%
  • Prohormone 40%
  27 Citationer (Scopus)

• Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

  Wewer Albrechtsen, N. J., Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, S. S., Meier, F., Niu, L., Santos, A., Keilhauer, E. C., Holst, J. J., Madsbad, S. & Mann, M., 26 dec. 2018, I: Cell Systems. 7, 6, s. 601-612

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  • Gastric Bypass 100%
  • Proteome 90%
  • Homeostasis 63%
  • Lipids 56%
  • Bariatric Surgery 48%
  31 Citationer (Scopus)

  40 Downloads (Pure)

• Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery

  Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J., & 2 flereZeng, R. & Wu, J-R., 2018, I: EBioMedicine. 28, s. 234-240 7 s.

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  • Gastric Bypass 100%
  • Type 2 Diabetes Mellitus 65%
  • Metabolite 61%
  • Weight 46%
  • Protein 35%
  6 Citationer (Scopus)

  179 Downloads (Pure)
• 2017

  A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

  Wewer Albrechtsen, N. J., Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, R. E., Asmar, M., Veedfald, S., Plamboeck, A., Knop, F. K., Vilsbøll, T., Madsbad, S., Nauck, M. A., Deacon, C. F., Bülow, J., Holst, J. J. & Hartmann, B., 1 sep. 2017, I: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, s. E284-E291

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  • Glucagon-Like Peptide 1 100%
  • Enzyme-Linked Immunosorbent Assay 60%
  • Type 2 Diabetes Mellitus 12%
  • Dipeptidyl Peptidase 4 11%
  • Dipeptidyl-Peptidase IV Inhibitors 11%
  6 Citationer (Scopus)

• Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

  Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N., & 9 flereIdorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., 7 nov. 2017, I: Cell Reports. 21, 6, s. 1452-1460

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  • Proglucagon 100%
  • Glucagon 85%
  • Insulin Derivative 64%
  • Insulin Secretion 62%
  • Blood Glucose 52%
  13 Citationer (Scopus)

  119 Downloads (Pure)

• Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle: The Liver-α-Cell Axis

  Holst, J. J., Wewer Albrechtsen, N. J., Pedersen, J. & Knop, F. K., 1 feb. 2017, I: Diabetes. 66, 2, s. 235-240 6 s.

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  • Glucagon 100%
  • Amino Acids 67%
  • Liver 49%
  • Necrolytic Migratory Erythema 48%
  • Glucagonoma 42%
  67 Citationer (Scopus)

• Glucagon-like peptide-1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP-1 receptors

  Ronn, J., Jensen, E. P., Wewer Albrechtsen, N. J., Holst, J. J. & Sorensen, C. M., dec. 2017, I: Physiological Reports. 5, 23, 14 s., e13503.

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  • Glucagon-Like Peptide-1 Receptor 100%
  • Renal Circulation 90%
  • Glucagon-Like Peptide 1 90%
  • Inbred SHR Rats 84%
  • Kidney 41%
  14 Citationer (Scopus)

  59 Downloads (Pure)

• Health care professionals from developing countries report educational benefits after an online diabetes course

  Wewer Albrechtsen, N. J., Poulsen, K. W., Svensson, L. Ø., Jensen, L., Holst, J. J. & Torekov, S. S., 31 maj 2017, I: B M C Medical Education. 17, 8 s., 97.

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  • Health care professionals 100%
  • chronic illness 90%
  • developing country 68%
  • participation 11%
  • questionnaire 7%
  9 Citationer (Scopus)

  70 Downloads (Pure)

• Increased liver fat content in totally pancreatectomised patients

  Bagger, J. I., Lund, A. B., Albrechtsen, N. J. W., Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, J. J., Vilsboll, T. & Knop, F. K., 2017, I: Diabetologia. 60, S1, s. S572-S573

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• On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat

  Kuhre, R. E., Christiansen, C. B., Saltiel, M. Y., Albrechtsen, N. J. W. & Holst, J. J., 3 dec. 2017, I: Physiological Reports. 5, 23, 13 s., e13507.

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  • Neurotensin 100%
  • Glucagon-Like Peptide 1 53%
  • Peptides 48%
  • Glucose 47%
  • Colon 30%
  21 Citationer (Scopus)

  73 Downloads (Pure)

• Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

  Hyltén-Cavallius, L., Iepsen, E. W., Wewer Albrechtsen, N. J., Svendstrup, M., Lubberding, A. F., Hartmann, B., Jespersen, T., Linneberg, A., Christiansen, M., Vestergaard, H., Pedersen, O., Holst, J. J., Kanters, J. K., Hansen, T. & Torekov, S. S., 2 maj 2017, I: Circulation. 135, 18, s. 1705-1719 15 s.

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  • Long QT Syndrome 100%
  • Incretins 99%
  • Potassium Channels 87%
  • Hypoglycemia 74%
  • Glucose 48%
  17 Citationer (Scopus)

  84 Downloads (Pure)

• Roles of increased glycemic variability, GLP-1 and glucagon in hypoglycaemia after Roux-en-Y gastric bypass

  Tharakan, G., Behary, P., Wewer Albrechtsen, N. J., Chahal, H., Kenkre, J., Miras, A. D., Ahmed, A. R., Holst, J. J., Bloom, S. R. & Tan, T. M. M., 1 dec. 2017, I: European Journal of Endocrinology. 177, s. 455-464 10 s.

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  • Glucagon-Like Peptide 1 100%
  • Gastric Bypass 97%
  • Glucagon 88%
  • Hypoglycemia 82%
  • Meals 34%
  26 Citationer (Scopus)

  59 Downloads (Pure)

• The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers

  Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Wewer Albrechtsen, N. J., Holst, J. J. & Bloom, S. R., 1 jul. 2017, I: The Journal of clinical endocrinology and metabolism. 102, 7, s. 2364-2372 9 s.

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  • Oxyntomodulin 100%
  • Peptide YY 90%
  • Glucagon-Like Peptide 1 82%
  • Subcutaneous Infusions 68%
  • Gastrointestinal Hormone 60%
  43 Citationer (Scopus)

  52 Downloads (Pure)

• The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

  Holst, J. J., Pedersen, J., Wewer Albrechtsen, N. J. & Knop, F. K., aug. 2017, I: Metabolic Syndrome and Related Disorders. 15, 6, s. 259-262 4 s.

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  • Incretins 100%
  • Type 2 Diabetes Mellitus 96%
  • Glucose 80%
  • Gastric Emptying 58%
  • Glucagon 53%
  6 Citationer (Scopus)

• Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

  Engelbrechtsen, L., Lundgren, J., Wewer Albrechtsen, N. J., Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, A. E., Madsbad, S., Holst, J. J., Vestergaard, H., Hansen, T. & Torekov, S. S., dec. 2017, I: Obesity Science & Practice. 3, 4, s. 425-433 9 s.

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  • Liraglutide 100%
  • Apolipoproteins B 79%
  • Cardiovascular Diseases 51%
  • Weight Loss 29%
  • Caloric Restriction 26%
  7 Citationer (Scopus)

  146 Downloads (Pure)

• Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

  Windeløv, J. A., Wewer Albrechtsen, N. J., Kuhre, R. E., Jepsen, S. L., Hornburg, D., Pedersen, J., Jensen, E. P., Galsgaard, K. D., Winther-Sørensen, M., Ørgaard, A., Deacon, C. F., Mann, M., Kissow, H., Hartmann, B. & Holst, J. J., 1 okt. 2017, I: Diabetologia. 60, 10, s. 2066-2075 10 s.

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  • Glucagon-Like Peptide 1 100%
  • Enzyme-Linked Immunosorbent Assay 26%
  • candoxatril 21%
  • Dipeptidyl Peptidase 4 14%
  • Peptide Fragments 7%
  22 Citationer (Scopus)
• 2016

  A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats

  Hoelmkjaer, K. M., Albrechtsen, N. J. W., Holst, J. J., Cronin, A. M., Nielsen, D. H., Mandrup-Poulsen, T. & Bjørnvad, C. R., 1 maj 2016, I: P L o S One. 11, 5, 18 s., e0154727.

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  • adipokines 100%
  • Secretion 99%
  • glucagon-like peptide 1 97%
  • Insulin 95%
  • Peptides 94%
  6 Citationer (Scopus)

  99 Downloads (Pure)

• Do glucagonomas always produce glucagon?

  Wewer Albrechtsen, N. J., Challis, B., Damjanov, I. & Holst, J. J., 1 feb. 2016, I: Bosnian Journal of Basic Medical Sciences. 16, 1, s. 1-7 7 s.

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  • Proglucagon 100%
  • Glucagonoma 98%
  • Glucagon 65%
  • Peptides 28%
  • Glicentin 16%
  7 Citationer (Scopus)

  53 Downloads (Pure)

• Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

  Albrechtsen, N. J. W., Kuhre, R. E., Windeløv, J. A., Ørgaard, A., Deacon, C. F., Kissow, H., Hartmann, B. & Holst, J. J., 1 aug. 2016, I: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, s. E302-E309 8 s.

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  • Glucagon 100%
  • Enzyme-Linked Immunosorbent Assay 67%
  • Arginine 53%
  • Hypnorm 38%
  • Glucose 36%
  16 Citationer (Scopus)

• Evidence of Extrapancreatic Glucagon Secretion in Man

  Lund, A., Bagger, J. I., Wewer Albrechtsen, N. J., Christensen, M., Grøndahl, M., Hartmann, B., Mathiesen, E. R., Hansen, C. P., Storkholm, J. H., van Hall, G., Rehfeld, J. F., Hornburg, D., Meissner, F., Mann, M., Larsen, S., Holst, J. J., Lauritsen, T. V. & Knop, F. K., mar. 2016, I: Diabetes. 65, 3, s. 585-597 13 s.

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  • Glucagon 100%
  • Glucose 45%
  • Pancreas 41%
  • Pancreatectomy 28%
  • Glucose Tolerance Test 24%
  89 Citationer (Scopus)