Clare Louise Hawkins

Publikation

Publikationer pr. år 2002 2002 2008 2009 2010 2012 2014 2016 2017 2018 2019 2019

• 68 Tidsskriftartikel
• 1 Bidrag til bog/antologi
• 1 Kommentar/debat
• 1 Konferenceabstrakt i tidsskrift
• 2 Mere
  • 1 Leder
  • 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  8-Chloroadenosine induces apoptosis in human coronary artery endothelial cells through the activation of the unfolded protein response

  Tang, V., Fu, S., Rayner, B. S. & Hawkins, C. L., sep. 2019, I: Redox Biology. 26, 11 s., UNSP 101274.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  9 Citationer (Scopus)

  3 Downloads (Pure)

• A Role for Chlorinated Nucleosides in the Perturbation of Macrophage Function and Promotion of Inflammation

  Macer-Wright, J. L., Stanley, N. R., Portman, N., Tan, J. T., Bursill, C., Rayner, B. S. & Hawkins, C. L., 17 jun. 2019, I: Chemical Research in Toxicology. 32, 6, s. 1223-1234

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nucleosides 100%
  • Cytidine 87%
  • Nucleoside 87%
  • Macrophages 66%
  • 8-chloroadenosine 60%
  2 Citationer (Scopus)

• Characterization of the cellular effects of myeloperoxidase-derived oxidants on H9c2 cardiac myoblasts

  Reyes, L., Hawkins, C. L. & Rayner, B. S., 15 apr. 2019, I: Nitric Oxide: Biology and Chemistry. 665, s. 132-142

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Cardiac Myoblasts 100%
  • Hypochlorous Acid 74%
  • Oxidants 59%
  • Peroxidase 54%
  • Reperfusion Injury 33%
  7 Citationer (Scopus)

• Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase

  Lim, Y. J., Foo, T. C., Yeung, A. W. S., Tu, X., Ma, Y., Hawkins, C. L., Witting, P. K., Jameson, G. N. L., Terentis, A. C. & Thomas, S. R., 19 feb. 2019, I: Biochemistry. 58, 7, s. 974-986

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • human indoleamine 2,3-dioxygenase 1 100%
  • Nitrite Reductases 78%
  • Indoleamine-Pyrrole 2,3,-Dioxygenase 64%
  • Nitrite 46%
  • Nitric Oxide 18%
  10 Citationer (Scopus)

• Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells

  Cai, H., Chuang, C. Y., Vanichkitrungruang, S., Hawkins, C. L. & Davies, M. J., apr. 2019, I: Free Radical Biology and Medicine. 134, s. 526-536

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  13 Citationer (Scopus)

• In Vitro Stimulation and Visualization of Extracellular Trap Release in Differentiated Human Monocyte-derived Macrophages

  Zhang, Y., Rayner, B. S., Jensen, M. & Hawkins, C. L., nov. 2019, I: Journal of Visualized Experiments. 153, e60541 .

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Macrophages 100%
  • Extracellular Traps 84%
  • Visualization 45%
  • Green 40%
  • Phorbol 40%
  2 Citationer (Scopus)

• Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

  Vanichkitrungruang, S., Chuang, C. Y., Hawkins, C. L., Hammer, A., Hoefler, G., Malle, E. & Davies, M. J., 20 maj 2019, I: Free Radical Biology and Medicine. 136, s. 118-134

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  13 Citationer (Scopus)
• 2018

  A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid

  Pan, G., Rayner, B., Zhang, Y., van Reyk, D. & Hawkins, C., 15 mar. 2018, I: Archives of Biochemistry and Biophysics. 642, s. 23-30 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Hypochlorous Acid 63%
  • Oxidants 50%
  • Peroxidase 46%
  8 Citationer (Scopus)

• A therapeutic role for selenoprotein T in reducing ischaemia/reperfusion injury in the heart?

  Hawkins, C. L., aug. 2018, I: Acta Physiologica. 223, 4, 3 s., e13106 .

  Publikation: Bidrag til tidsskrift › Leder › peer review

  1 Citationer (Scopus)

• Cellular responses to radical propagation from ion-implanted plasma polymer surfaces

  Stewart, C. A. C., Akhavan, B., Santos, M., Hung, J., Hawkins, C. L., Bao, S., Wise, S. G. & Bilek, M. M. M., 31 okt. 2018, I: Applied Surface Science. 456, s. 701-710

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Implanted Ion 100%
  • Polymer films 93%
  • Plasmas 65%
  • Ions 65%
  • Polymers 51%
  8 Citationer (Scopus)

• Protein carbamylation: a key driver of vascular calcification during chronic kidney disease

  Hawkins, C. L., jul. 2018, I: Kidney International. 94, 1, s. 12-14

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  • Protein Carbamylation 100%
  • Vascular Calcification 79%
  • Chronic Renal Insufficiency 55%
  • diphosphoric acid 26%
  • Phosphoric Diester Hydrolases 23%
  5 Citationer (Scopus)

• Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation

  Rayner, B. S., Zhang, Y., Brown, B. E., Reyes, L., Cogger, V. C. & Hawkins, C. L., dec. 2018, I: Free Radical Biology and Medicine. 129, s. 25-34

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hypochlorous Acid 100%
  • Extracellular Traps 98%
  • Macrophages 48%
  • Phorbol 15%
  • Leukocytes 13%
  11 Citationer (Scopus)

• The dys-regulation of anti-oxidant defense via an impairment of Nrf2 response in the pathology of Friedreich's ataxia: [Meeting Abstract]

  Chiang, S., Anzovino, A., Brown, B. E., Hawkins, C. L., Richardson, D. R. & Huang, M. L. -H., 2018, I: Free Radical Biology and Medicine. 120, s. S35-S35 OP-19 .

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
• 2017

  Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes

  Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, M. J. & Hawkins, C. L., 1 aug. 2017, I: Redox Biology. 12, s. 872-882 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chloramines 100%
  • altritol 88%
  • Selenium Compounds 88%
  • Thioredoxin-Disulfide Reductase 79%
  • Glutathione Reductase 68%
  17 Citationer (Scopus)

  102 Downloads (Pure)

• CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis

  Ridiandries, A., Tan, J. T. M., Ravindran, D., Williams, H., Medbury, H. J., Lindsay, L., Hawkins, C., Prosser, H. C. G. & Bursill, C. A., mar. 2017, I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31, 3, s. 1179-1192 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Physiologic Neovascularization 100%
  • Pathologic Neovascularization 90%
  • CC Chemokines 81%
  • Hypoxia 50%
  • Angiogenic 46%
  6 Citationer (Scopus)

• Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction

  Abdo, A., Rayner, B. S., van Reyk, D. M. & Hawkins, C. L., okt. 2017, I: Redox Biology. 13, s. 623-632 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Low-Density Lipoprotein 100%
  • Oxidants 89%
  • LDL Lipoproteins 88%
  • Peroxidase 82%
  • Hypochlorous Acid 76%
  16 Citationer (Scopus)

  65 Downloads (Pure)

• Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis

  Anzovino, A., Chiang, S., Brown, B. E., Hawkins, C. L., Richardson, D. R. & Huang, M. L-H., dec. 2017, I: American Journal of Pathology. 187, 12, s. 2858-2875 18 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Friedreich Ataxia 100%
  • Glycogen Synthase Kinase 3 96%
  • frataxin 89%
  • Skeletal Muscle 56%
  • Up-Regulation 51%
  30 Citationer (Scopus)

• Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function

  Indo, H. P., Hawkins, C. L., Nakanishi, I., Matsumoto, K-I., Matsui, H., Suenaga, S., Davies, M. J., St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Bind 240. s. 439-456 18 s. (Handbook of Experimental Pharmacology, Bind 240).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Superoxides 100%
  • Reactive Oxygen Species 79%
  • Signal Transduction 58%
  • Mitochondria 41%
  • Cell Death 37%
  28 Citationer (Scopus)
• 2016

  A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity

  Lok, H. C., Sahni, S., Jansson, P. J., Kovacevic, Z., Hawkins, C. L. & Richardson, D. R., 30 dec. 2016, I: The Journal of Biological Chemistry. 291, 53, s. 27042-27061 20 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • multidrug resistance-associated protein 1 100%
  • Nitric Oxide 82%
  • Macrophages 60%
  • Glutathione 58%
  • dinitrosyl iron complex 55%
  23 Citationer (Scopus)

• Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

  Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, M. J. & Hawkins, C. L., 1 maj 2016, I: Free Radical Biology & Medicine. 94, s. 88-98 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Glycolysis 50%
  • Oxidants 50%
  • Peroxidase 46%
  23 Citationer (Scopus)

• Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space

  Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, C. L., Davies, M. J., Clair, D. K. S. & Mukai, C., 23 dec. 2016, I: Scientific Reports. 6, 10 s., 39015.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mitochondrial RNA 100%
  • Astronauts 92%
  • Oxidation-Reduction 64%
  • Homeostasis 49%
  • Mitochondrial DNA 47%
  12 Citationer (Scopus)

  71 Downloads (Pure)

• Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

  Tweeddale, H. J., Hawkins, C. L., Janmie, J. F., Truscott, R. J. W. & Davies, M. J., 2 okt. 2016, I: Free Radical Research. 50, 10, s. 1116-1130 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Crystallins 100%
  • Tryptophan 81%
  • Lenses 72%
  • Cataract 71%
  • 3-Hydroxyanthranilic Acid 67%
  17 Citationer (Scopus)

• Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

  Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, M. J. & Hawkins, C. L., dec. 2016, I: P L o S One. 11, 12, 16 s., e0168844.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Macrophages 100%
  • Cathepsins 98%
  • Lipoproteins 95%
  • Atherosclerosis 94%
  • Macrophage 92%
  10 Citationer (Scopus)

• β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

  Karimi Galougahi, K., Liu, C-C., Garcia, A., Gentile, C., Fry, N. A., Hamilton, E. J., Hawkins, C. L. & Figtree, G. A., 1 feb. 2016, I: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 5, 2, e002824.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nitric Oxide Synthase Type III 100%
  • disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate 93%
  • Adrenergic Agents 85%
  • Oxidation-Reduction 84%
  • Hyperglycemia 80%
  18 Citationer (Scopus)
• 2015

  Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion

  Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, C. L., Davies, M. J., Yarana, C., Clair, D. K. S. & Majima, H. J., 1 jul. 2015, I: Journal of Clinical Biochemistry and Nutrition. 57, 1, s. 13-20 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Talin 100%
  • Superoxide 66%
  • Superoxide Dismutase 62%
  • Actins 57%
  • Stomach 48%
  5 Citationer (Scopus)

• Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage

  Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, M. J. & Hawkins, C. L., 2 apr. 2015, I: Free Radical Biology & Medicine. 84, s. 279-288 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chloramines 100%
  • Selenium Compounds 88%
  • Sulfur Compounds 66%
  • Oxidants 57%
  • Hypochlorous Acid 54%
  18 Citationer (Scopus)
• 2014

  Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells

  Rayner, B. S., Love, D. T. & Hawkins, C. L., jun. 2014, I: Free Radical Biology & Medicine. 71, s. 240-55 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Rådgivning › peer review

  • Oxidants 100%
  • Mammalian Cell 99%
  • Peroxidase 92%
  • Hypothiocyanous Acid 61%
  • Acids 54%
  66 Citationer (Scopus)

• Detection and characterisation of radicals in biological materials using EPR methodology

  Hawkins, C. L. & Davies, M. J., feb. 2014, I: B B A - Reviews on Cancer. 1840, 2, s. 708-21 14 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Electron Spin Resonance Spectroscopy 100%
  • Spectrum Analysis 37%
  • Hydroxylamines 36%
  • Metals 33%
  • Ions 32%
  122 Citationer (Scopus)

• Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

  Galougahi, K. K., Liu, C-C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, M. J., Hawkins, C. L., Rasmussen, H. H. & Figtree, G. A., 2014, I: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, s. e000731

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nitric Oxide Synthase Type III 100%
  • NADP 95%
  • Angiotensin II 85%
  • Oxidoreductases 80%
  • Nitric Oxide 28%
  51 Citationer (Scopus)

• Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides

  Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, C. L. & Davies, M. J., maj 2014, I: Free Radical Biology & Medicine. 70, s. 96-105 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oxidants 100%
  • Peroxidase 92%
  • Neutrophils 75%
  • Inhibitory Concentration 50 43%
  • Hypochlorous Acid 34%
  28 Citationer (Scopus)

• Role of cyanate in the induction of vascular dysfunction during uremia: more than protein carbamylation?

  Hawkins, C. L., 5 nov. 2014, I: Kidney International. 86, 5, s. 875-7 3 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Cyanates 100%
  • Protein Carbamylation 97%
  • Uremia 70%
  • Blood Vessels 34%
  • Chronic Renal Insufficiency 18%
  6 Citationer (Scopus)

• Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants

  Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, M. J., Hawkins, C. L. & Ashby, M. T., 15 dec. 2014, I: Archives of Biochemistry and Biophysics. 564, s. 1-11 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • thiocyanate 100%
  • Tryptophan 73%
  • Oxidants 71%
  • Peroxidases 53%
  • Sulfhydryl Compounds 37%
  6 Citationer (Scopus)
• 2013

  Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

  Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, M. J. & Hawkins, C. L., dec. 2013, I: Free Radical Biology & Medicine. 65, s. 1352-62 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Hypochlorous Acid 69%
  • Oxidants 50%
  • Peroxidase 46%
  34 Citationer (Scopus)

• Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)

  Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K-A., Davies, M. J. & Hawkins, C. L., 15 jan. 2013, I: Biochemical Journal. 449, 2, s. 531-42 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Hypochlorous Acid 69%
  • High-Density Lipoprotein 61%
  • Apolipoprotein 59%
  42 Citationer (Scopus)
• 2012

  Hypothiocyanous acid - benign or deadly?

  Barrett, T. J. & Hawkins, C. L., 20 feb. 2012, I: Chemical Research in Toxicology. 25, 2, s. 263-73 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Bacteriostatic 64%
  • Oxidants 50%
  • Mammalian Cell 50%
  63 Citationer (Scopus)

• Identification of proteins susceptible to thiol oxidation in endothelial cells exposed to hypochlorous acid and N-chloramines

  Summers, F. A., Forsman Quigley, A. & Hawkins, C. L., 24 aug. 2012, I: Biochemical and Biophysical Research Communications. 425, 2, s. 157-61 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chloramines 100%
  • Hypochlorous Acid 79%
  • Sulfhydryl Compounds 59%
  • Thiol 46%
  • Endothelial Cells 40%
  26 Citationer (Scopus)

• Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

  Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, M. J. & Hawkins, C. L., 15 mar. 2012, I: Free Radical Biology & Medicine. 52, 6, s. 1075-85 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Sulfenic Acids 89%
  • thiocyanate 70%
  • Sulfenic Acid 68%
  42 Citationer (Scopus)

• Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes

  Lok, H. C., Suryo Rahmanto, Y., Hawkins, C. L., Kalinowski, D. S., Morrow, C. S., Townsend, A. J., Ponka, P. & Richardson, D. R., 2 jan. 2012, I: The Journal of Biological Chemistry. 287, 1, s. 607-18 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • dinitrosyl iron complex 100%
  • Dinitrosyl-Iron Complex 88%
  • Glutathione S-Transferase pi 83%
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 62%
  • Glutathione Transferase 60%
  43 Citationer (Scopus)

• Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

  Pattison, D. I., Davies, M. J. & Hawkins, C. L., aug. 2012, I: Free Radical Research. 46, 8, s. 975-95 21 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypothiocyanous acid 100%
  • Hypothiocyanous Acid 92%
  • Hypochlorous Acid 69%
  • Oxidants 50%
  • Peroxidase 46%
  102 Citationer (Scopus)

• Reduced circulating oxidized LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert syndrome

  Boon, A-C., Hawkins, C. L., Bisht, K., Coombes, J. S., Bakrania, B., Wagner, K-H. & Bulmer, A. C., 15 maj 2012, I: Free Radical Biology & Medicine. 52, 10, s. 2120-7 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oxidised LDL 100%
  • Gilbert Reaction 99%
  • Gilbert Disease 93%
  • Bilirubin 71%
  • Sulfhydryl Compounds 65%
  62 Citationer (Scopus)
• 2011

  Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

  Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, C. L. & Davies, M. J., 15 jan. 2011, I: Free Radical Biology & Medicine. 50, 2, s. 389-99 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Amino Acids, Peptides, and Proteins 100%
  • ATP dependent 26S protease 75%
  • Hydroperoxide 55%
  • Hydrogen Peroxide 54%
  • Decomposition 34%
  15 Citationer (Scopus)

• High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

  Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, C. L. & Davies, M. J., 1 nov. 2011, I: Free Radical Biology & Medicine. 51, 9, s. 1815-22 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • thiocyanate 100%
  • Sulfhydryl Compounds 74%
  • Thiocyanate 69%
  • Peroxidase 66%
  • Smokers 58%
  53 Citationer (Scopus)

• The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity

  Yu, Y., Suryo Rahmanto, Y., Hawkins, C. L. & Richardson, D. R., jun. 2011, I: Molecular Pharmacology. 79, 6, s. 921-31 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone 100%
  • di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone 81%
  • Thiosemicarbazones 68%
  • Ribonucleotide Reductases 56%
  • Chelating Agents 45%
  38 Citationer (Scopus)
• 2010

  Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents

  Stanley, N. R., Pattison, D. I. & Hawkins, C. L., 19 jul. 2010, I: Chemical Research in Toxicology. 23, 7, s. 1293-302 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chloramines 100%
  • Hypochlorous Acid 79%
  • DNA 30%
  • 8-chloro-2'-deoxyguanosine 25%
  • 5-chloro-2'-deoxycytidine 22%
  52 Citationer (Scopus)

• Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations

  Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, C. L., Rees, M. D. & Davies, M. J., 15 apr. 2010, I: Biochemical Pharmacology. 79, 8, s. 1156-64 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hypochlorous Acid 100%
  • Paracetamol 92%
  • Acetaminophen 80%
  • Oxidants 79%
  • Peroxidase 73%
  50 Citationer (Scopus)

• Cellular effects of peptide and protein hydroperoxides

  Rahmanto, A. S., Morgan, P. E., Hawkins, C. L. & Davies, M. J., 15 apr. 2010, I: Free Radical Biology & Medicine. 48, 8, s. 1071-8 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydroperoxide 100%
  • Hydrogen Peroxide 97%
  • Sulfhydryl Compounds 78%
  • Peptides 62%
  • Peptide 56%
  36 Citationer (Scopus)

• Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

  Rahmanto, A. S., Morgan, P. E., Hawkins, C. L. & Davies, M. J., 30 nov. 2010, I: Free Radical Biology & Medicine. 49, 10, s. 1505-15 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oxidants 100%
  • Hydroperoxide 98%
  • Hydrogen Peroxide 95%
  • Sulfhydryl Compounds 69%
  • Thioredoxin 60%
  27 Citationer (Scopus)

• The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study

  Jansson, P. J., Hawkins, C. L., Lovejoy, D. B. & Richardson, D. R., nov. 2010, I: Journal of Inorganic Biochemistry. 104, 11, s. 1224-8 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone 100%
  • Hydroxyl Radical 55%
  • Oxidation-Reduction 48%
  • EPR Spectroscopy 43%
  • Iron 42%
  47 Citationer (Scopus)

• The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

  Lane, A. E., Tan, J. T. M., Hawkins, C. L., Heather, A. K. & Davies, M. J., 15 aug. 2010, I: Biochemical Journal. 430, 1, s. 161-9 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • hypobromous acid 100%
  • Protein Tyrosine Phosphatases 84%
  • Hypochlorous Acid 73%
  • Oxidants 71%
  • Mitogen-Activated Protein Kinases 68%
  59 Citationer (Scopus)
• 2009

  Quantification of protein modification by oxidants

  Hawkins, C. L., Morgan, P. E. & Davies, M. J., 15 apr. 2009, I: Free Radical Biology & Medicine. 46, 8, s. 965-88 24 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oxidants 100%
  • Modification 53%
  • Absolute Yield 39%
  • Protein 39%
  • Proteins 35%
  319 Citationer (Scopus)