Andres Lopez-Contreras

Panum Instituttet, Blegdamsvej 3, 2200 København N

Publikationer pr. år

Primære forskningsområder

DNA damage and DNA repair, Replication Stress, Mouse models of cancer and ageing.

Aktuel forskning

Exploring the impact of Replication Stress on Ageing and Cancer This project is financed from the Danish National Research Program “Sapere Aude – DFF Starting Grant”

Identification of novel targets for the BRCA1 ubiquitin ligase activity. This project is funded by a KBVU Project from the Danish Cancer Society.

Chromosomal Common Fragile Sites: Unravelling their biological functions and the basis of their instability This project is funded by the European Research Council (ERC-2015-StG)

Participants: Andres J Lopez-Contreras, group leader Alexandra Avram, lab technician Mauro Sbroggió, postdoc Stephanie Munk, postdoc Eliene Albers, PhD student David Pladevall Morera, PhD student

If you are interested in joining our lab, we want to hear about you and your ideas! Please, send an e-mail to [email protected] including your CV and a motivation letter.

Collaborators

Dr. Oscar Fernandez-Capetillo, Spanish National Cancer Research Center (CNIO), Madrid, Spain
Prof. Ian D. Hickson, Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark
Prof. Rafael Peñafiel-Garcia, University of Murcia, Spain
Dr. Javier Muñoz, Spanish National Cancer Research Center (CNIO), Madrid, Spain
Dr. Andre Nussenzweig, National Cancer Institute, National Institutes of Health, Bethesda, USA
Dr. Jeremy A. Daniel, Center for Protein Research, University of Copenhagen, Denmark.
Jesper V. Olsen, CPR, Copenhagen, Denmark (mass spectrometry for quantitative proteomics)
Lene J. Rasmussen, CEHA, Copenhagen, Denmark (genomic instability and mitochondrial function)

Ekspertise relateret til FN’s Verdensmål

I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:

Emneord

Det Sundhedsvidenskabelige Fakultet
DNA damage
DNA repair
Replication Stress
Mouse models of cancer and ageing

Fingeraftryk

Dyk ned i forskningsemnerne, hvor Andres Lopez-Contreras er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.

6 Lignende profiler

32 Tidsskriftartikel
1 Bidrag til bog/antologi
1 Review

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Pladevall-Morera, D., Munk, S., Ingham, A., Garribba, L., Albers, E., Liu, Y., Olsen, J. V. & Lopez-Contreras, A. J., 1 sep. 2019, I: Nucleic Acids Research. 47, 15, s. 8004-8018 15 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
9 Citationer (Scopus)

14 Downloads (Pure)
TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress
Lafarga, V., Sung, H.-M., Haneke, K., Roessig, L., Pauleau, A.-L., Bruer, M., Rodriguez-Acebes, S., Lopez-Contreras, A. J., Gruss, O. J., Erhardt, S., Mendez, J., Fernandez-Capetillo, O. & Stoecklin, G., jan. 2019, I: EMBO Reports. 20, 1
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
6 Citationer (Scopus)
Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality
Albers, E., Sbroggiò, M., Pladevall-Morera, D., Bizard, A. H., Avram, A., Gonzalez, P., Martin-Gonzalez, J., Hickson, I. D. & Lopez-Contreras, A. J., 2018, I: Cell Reports. 24, 12, s. 3274-3284 11 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
10 Citationer (Scopus)

69 Downloads (Pure)
New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility
Lambertos, A., Ramos-Molina, B., López-Contreras, A. J., Cremades, A. & Peñafiel, R., 2018, I: PLoS ONE. 13, 12, 22 s., e0209202.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
3 Citationer (Scopus)

5 Downloads (Pure)
The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase
Lambertos, A., Ramos-Molina, B., Cerezo, D., López-Contreras, A. J. & Peñafiel, R., mar. 2018, I: Biochimica et Biophysica Acta - General Subjects. 1862, 3, s. 365-376 12 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
4 Citationer (Scopus)
A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot
Albers, E., Sbroggiò, M., Martin Gonzalez, J., Avram, A. I., Munk, S. & Lopez-Contreras, A. J., 1 jun. 2017, I: Transgenic Research. 26, 3, s. 429-434 6 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
4 Citationer (Scopus)
Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress
Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, T. S., Franciosa, G., von Stechow, L., Lopez-Contreras, A. J., Vertegaal, A. C. O. & Olsen, J. V., 2017, I: Cell Reports. 21, 2, s. 546-558 13 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
15 Citationer (Scopus)

81 Downloads (Pure)
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas
Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D. & Sarrazin, S. & 18 flere, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, A. J., Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 nov. 2016, I: Cell. 167, 5, s. 1264–1280.e18
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
44 Citationer (Scopus)