Saliva: a new opportunity for fluid biopsy
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Saliva : a new opportunity for fluid biopsy. / Huang, Zhijie; Yang, Xiaoxia; Huang, Yisheng; Tang, Zhengming; Chen, Yuanxin; Liu, Hongyu; Huang, Mingshu; Qing, Ling; Li, Li; Wang, Qin; Jie, Zhuye; Jin, Xin; Jia, Bo.
I: Clinical Chemistry and Laboratory Medicine, Bind 61, Nr. 1, 2022.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Saliva
T2 - a new opportunity for fluid biopsy
AU - Huang, Zhijie
AU - Yang, Xiaoxia
AU - Huang, Yisheng
AU - Tang, Zhengming
AU - Chen, Yuanxin
AU - Liu, Hongyu
AU - Huang, Mingshu
AU - Qing, Ling
AU - Li, Li
AU - Wang, Qin
AU - Jie, Zhuye
AU - Jin, Xin
AU - Jia, Bo
PY - 2022
Y1 - 2022
N2 - Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA, proteins, metabolites and microbiota, which can be used for the screening and diagnosis of many diseases. In addition, saliva has the characteristics of simple collection, non-invasive and convenient storage, which gives it the potential to replace blood as a new main body of fluid biopsy, and it is an excellent biological diagnostic fluid. This review integrates recent studies and summarizes the research contents of salivaomics and the research progress of saliva in early diagnosis of oral and systemic diseases. This review aims to explore the value and prospect of saliva diagnosis in clinical application.
AB - Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA, proteins, metabolites and microbiota, which can be used for the screening and diagnosis of many diseases. In addition, saliva has the characteristics of simple collection, non-invasive and convenient storage, which gives it the potential to replace blood as a new main body of fluid biopsy, and it is an excellent biological diagnostic fluid. This review integrates recent studies and summarizes the research contents of salivaomics and the research progress of saliva in early diagnosis of oral and systemic diseases. This review aims to explore the value and prospect of saliva diagnosis in clinical application.
KW - biomarkers
KW - oral diseases
KW - salivaomics
KW - salivary diagnosis
KW - systemic diseases
KW - SQUAMOUS-CELL CARCINOMA
KW - NECROSIS-FACTOR-ALPHA
KW - ORAL LICHEN-PLANUS
KW - ACUTE MYOCARDIAL-INFARCTION
KW - TYROSINE KINASE INHIBITORS
KW - C-REACTIVE PROTEIN
KW - POTENTIAL BIOMARKERS
KW - BREAST-CANCER
KW - PROMOTER HYPERMETHYLATION
KW - INTERFERON-GAMMA
U2 - 10.1515/cclm-2022-0793
DO - 10.1515/cclm-2022-0793
M3 - Review
C2 - 36285724
VL - 61
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
SN - 1434-6621
IS - 1
ER -
ID: 325837563