Whipples sygdom

Raquel Martin-Iguacel; Pia Susanne Clark; Toke S Barfod

Whipples sygdom

Raquel Martin-Iguacel, Pia Susanne Clark, Toke S Barfod

Department of Clinical Medicine

Abstract

Whipple's disease (WD) is a rare, chronic, systemic infection caused by the bacterium Tropheryma whipplei. New molecular techniques and epidemiological data over the latest decade have contributed to better understanding of this infection. The classical form of WD is characterized by arthritis followed years after by diarrhoea, weight loss and malabsorption but other clinical forms without intestinal involvement have been described. Prompt recognition and treatment of the infection is important, as the disease can be fatal if untreated. New studies are required to establish the optimal therapy regimen.

Original language	Danish
Article number	V05130309
Journal	Ugeskrift for Laeger
Volume	177
Issue number	1
Pages (from-to)	57-60
Number of pages	4
ISSN	0041-5782
Publication status	Published - 6 Jan 2014

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Cite this

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AB - Whipple's disease (WD) is a rare, chronic, systemic infection caused by the bacterium Tropheryma whipplei. New molecular techniques and epidemiological data over the latest decade have contributed to better understanding of this infection. The classical form of WD is characterized by arthritis followed years after by diarrhoea, weight loss and malabsorption but other clinical forms without intestinal involvement have been described. Prompt recognition and treatment of the infection is important, as the disease can be fatal if untreated. New studies are required to establish the optimal therapy regimen.

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