Whipples sygdom

Raquel Martin-Iguacel; Pia Susanne Clark; Toke S Barfod

Whipples sygdom

Raquel Martin-Iguacel, Pia Susanne Clark, Toke S Barfod

Institut for Klinisk Medicin

Abstract

Whipple's disease (WD) is a rare, chronic, systemic infection caused by the bacterium Tropheryma whipplei. New molecular techniques and epidemiological data over the latest decade have contributed to better understanding of this infection. The classical form of WD is characterized by arthritis followed years after by diarrhoea, weight loss and malabsorption but other clinical forms without intestinal involvement have been described. Prompt recognition and treatment of the infection is important, as the disease can be fatal if untreated. New studies are required to establish the optimal therapy regimen.

Originalsprog	Dansk
Artikelnummer	V05130309
Tidsskrift	Ugeskrift for Laeger
Vol/bind	177
Udgave nummer	1
Sider (fra-til)	57-60
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 6 jan. 2014

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Citationsformater

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N2 - Whipple's disease (WD) is a rare, chronic, systemic infection caused by the bacterium Tropheryma whipplei. New molecular techniques and epidemiological data over the latest decade have contributed to better understanding of this infection. The classical form of WD is characterized by arthritis followed years after by diarrhoea, weight loss and malabsorption but other clinical forms without intestinal involvement have been described. Prompt recognition and treatment of the infection is important, as the disease can be fatal if untreated. New studies are required to establish the optimal therapy regimen.

AB - Whipple's disease (WD) is a rare, chronic, systemic infection caused by the bacterium Tropheryma whipplei. New molecular techniques and epidemiological data over the latest decade have contributed to better understanding of this infection. The classical form of WD is characterized by arthritis followed years after by diarrhoea, weight loss and malabsorption but other clinical forms without intestinal involvement have been described. Prompt recognition and treatment of the infection is important, as the disease can be fatal if untreated. New studies are required to establish the optimal therapy regimen.

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