Typing of two Middle Eastern populations with the Precision ID Ancestry Panel.

Ditte Mikkelsen Truelsen; Maryam Sharafi Farzad; Helle Smidt Mogensen; Vania Pereira; Claus Børsting; Niels Morling

doi:10.1016/j.fsigss.2017.09.133

Typing of two Middle Eastern populations with the Precision ID Ancestry Panel.

Ditte Mikkelsen Truelsen, Maryam Sharafi Farzad, Helle Smidt Mogensen, Vania Pereira, Claus Børsting, Niels Morling

Section of Forensic Genetics

5 Citations (Scopus)

Abstract

Ancestry informative markers have a great potential for ancestry inference in forensic genetic casework. However, applying ancestry inference in casework requires sufficient allele frequency data on as many populations as possible to allow the determination of biogeographical origin. Therefore, Turkish and Iranian individuals were SNP typed with Massively Parallel Sequencing with the Precision ID Ancestry Panel (Thermo Fisher Scientific) to assess whether it was possible to differentiate geographically proximate populations in the Middle East using this kit. Analyses showed that it were not possible to separate the two populations and neither was it possible to separate them from European and South-Central Asian populations. The two Middle Eastern populations were highly admixed with components from both Europe and South-Central Asia. Thus, it is important to identify genetic markers that are characteristic of the various Middle Eastern populations.

Original language	English
Journal	Forensic Science International: Genetics. Supplement Series
Volume	6
Pages (from-to)	e302-e303
ISSN	1875-1768
DOIs	https://doi.org/10.1016/j.fsigss.2017.09.133
Publication status	Published - Dec 2017

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title = "Typing of two Middle Eastern populations with the Precision ID Ancestry Panel.",

abstract = "Ancestry informative markers have a great potential for ancestry inference in forensic genetic casework. However, applying ancestry inference in casework requires sufficient allele frequency data on as many populations as possible to allow the determination of biogeographical origin. Therefore, Turkish and Iranian individuals were SNP typed with Massively Parallel Sequencing with the Precision ID Ancestry Panel (Thermo Fisher Scientific) to assess whether it was possible to differentiate geographically proximate populations in the Middle East using this kit. Analyses showed that it were not possible to separate the two populations and neither was it possible to separate them from European and South-Central Asian populations. The two Middle Eastern populations were highly admixed with components from both Europe and South-Central Asia. Thus, it is important to identify genetic markers that are characteristic of the various Middle Eastern populations.",

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T1 - Typing of two Middle Eastern populations with the Precision ID Ancestry Panel.

AU - Truelsen, Ditte Mikkelsen

AU - Farzad, Maryam Sharafi

AU - Mogensen, Helle Smidt

AU - Pereira, Vania

AU - Børsting, Claus

AU - Morling, Niels

PY - 2017/12

Y1 - 2017/12

N2 - Ancestry informative markers have a great potential for ancestry inference in forensic genetic casework. However, applying ancestry inference in casework requires sufficient allele frequency data on as many populations as possible to allow the determination of biogeographical origin. Therefore, Turkish and Iranian individuals were SNP typed with Massively Parallel Sequencing with the Precision ID Ancestry Panel (Thermo Fisher Scientific) to assess whether it was possible to differentiate geographically proximate populations in the Middle East using this kit. Analyses showed that it were not possible to separate the two populations and neither was it possible to separate them from European and South-Central Asian populations. The two Middle Eastern populations were highly admixed with components from both Europe and South-Central Asia. Thus, it is important to identify genetic markers that are characteristic of the various Middle Eastern populations.

AB - Ancestry informative markers have a great potential for ancestry inference in forensic genetic casework. However, applying ancestry inference in casework requires sufficient allele frequency data on as many populations as possible to allow the determination of biogeographical origin. Therefore, Turkish and Iranian individuals were SNP typed with Massively Parallel Sequencing with the Precision ID Ancestry Panel (Thermo Fisher Scientific) to assess whether it was possible to differentiate geographically proximate populations in the Middle East using this kit. Analyses showed that it were not possible to separate the two populations and neither was it possible to separate them from European and South-Central Asian populations. The two Middle Eastern populations were highly admixed with components from both Europe and South-Central Asia. Thus, it is important to identify genetic markers that are characteristic of the various Middle Eastern populations.

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DO - 10.1016/j.fsigss.2017.09.133

M3 - Conference article

SN - 1875-1768

VL - 6

SP - e302-e303

JO - Forensic Science International: Genetics. Supplement Series

JF - Forensic Science International: Genetics. Supplement Series

ER -

Typing of two Middle Eastern populations with the Precision ID Ancestry Panel.

Abstract

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