Tumorcelledissociering som prognostisk markør ved kolorektal cancer

Louise Klarskov; Ulla Højholt Engel; Anne Mellon Mogensen; Helle Lone Jensen; Susanne Holck; Louise Klarskov; Ulla Engel; Anne Mellon Mogensen; Helle Lone Jensen; Susanne Holck

Tumorcelledissociering som prognostisk markør ved kolorektal cancer

Translated title of the contribution: Tumour-cell dissociation as a prognostic marker in colorectal cancer

Louise Klarskov, Ulla Højholt Engel, Anne Mellon Mogensen, Helle Lone Jensen, Susanne Holck, Louise Klarskov, Ulla Engel, Anne Mellon Mogensen, Helle Lone Jensen, Susanne Holck

Department of Clinical Medicine

Abstract

The invasive front of the colorectal carcinoma (CRC) in some cases displays budding, characterized by groups of up to five tumour cells. In 2006, budding was introduced in the Danish Colorectal Cancer Group's (DCCG) and the Danish Society of Pathology and Cytology's (DSPAC) CRC register form. Based on a literature survey, molecular mechanisms that may contribute to budding are reviewed, as is the mode by which this process is registered and its putative clinical significance. Despite diverse modes of budding registration, its significance as a prognostic marker has consistently been substantiated. Additionally, data on budding may prove of value in patient management.

Translated title of the contribution	Tumour-cell dissociation as a prognostic marker in colorectal cancer
Original language	Danish
Journal	Ugeskrift for læger
Volume	171
Issue number	39
Pages (from-to)	2812-2817
Number of pages	6
ISSN	0041-5782
Publication status	Published - 2009

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Cite this

@article{952fa400aac911df928f000ea68e967b,

title = "Tumorcelledissociering som prognostisk mark{\o}r ved kolorektal cancer",

abstract = "The invasive front of the colorectal carcinoma (CRC) in some cases displays budding, characterized by groups of up to five tumour cells. In 2006, budding was introduced in the Danish Colorectal Cancer Group's (DCCG) and the Danish Society of Pathology and Cytology's (DSPAC) CRC register form. Based on a literature survey, molecular mechanisms that may contribute to budding are reviewed, as is the mode by which this process is registered and its putative clinical significance. Despite diverse modes of budding registration, its significance as a prognostic marker has consistently been substantiated. Additionally, data on budding may prove of value in patient management. Udgivelsesdato: 2009-Sep",

author = "Louise Klarskov and Engel, {Ulla H{\o}jholt} and Mogensen, {Anne Mellon} and Jensen, {Helle Lone} and Susanne Holck and Louise Klarskov and Ulla Engel and Mogensen, {Anne Mellon} and Jensen, {Helle Lone} and Susanne Holck",

note = "Keywords: Colorectal Neoplasms; Humans; Neoplasm Invasiveness; Prognosis; Risk Factors; Tumor Markers, Biological",

year = "2009",

language = "Dansk",

volume = "171",

pages = "2812--2817",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "39",

}

TY - JOUR

T1 - Tumorcelledissociering som prognostisk markør ved kolorektal cancer

AU - Klarskov, Louise

AU - Engel, Ulla Højholt

AU - Mogensen, Anne Mellon

AU - Jensen, Helle Lone

AU - Holck, Susanne

AU - Klarskov, Louise

AU - Engel, Ulla

AU - Mogensen, Anne Mellon

AU - Jensen, Helle Lone

AU - Holck, Susanne

N1 - Keywords: Colorectal Neoplasms; Humans; Neoplasm Invasiveness; Prognosis; Risk Factors; Tumor Markers, Biological

PY - 2009

Y1 - 2009

N2 - The invasive front of the colorectal carcinoma (CRC) in some cases displays budding, characterized by groups of up to five tumour cells. In 2006, budding was introduced in the Danish Colorectal Cancer Group's (DCCG) and the Danish Society of Pathology and Cytology's (DSPAC) CRC register form. Based on a literature survey, molecular mechanisms that may contribute to budding are reviewed, as is the mode by which this process is registered and its putative clinical significance. Despite diverse modes of budding registration, its significance as a prognostic marker has consistently been substantiated. Additionally, data on budding may prove of value in patient management. Udgivelsesdato: 2009-Sep

AB - The invasive front of the colorectal carcinoma (CRC) in some cases displays budding, characterized by groups of up to five tumour cells. In 2006, budding was introduced in the Danish Colorectal Cancer Group's (DCCG) and the Danish Society of Pathology and Cytology's (DSPAC) CRC register form. Based on a literature survey, molecular mechanisms that may contribute to budding are reviewed, as is the mode by which this process is registered and its putative clinical significance. Despite diverse modes of budding registration, its significance as a prognostic marker has consistently been substantiated. Additionally, data on budding may prove of value in patient management. Udgivelsesdato: 2009-Sep

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 171

SP - 2812

EP - 2817

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 39

ER -

Tumorcelledissociering som prognostisk markør ved kolorektal cancer

Abstract

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