Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis

L Fugger; N Morling; M Sandberg-Wollheim; L P Ryder; A Svejgaard

Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis

L Fugger, N Morling, M Sandberg-Wollheim, L P Ryder, A Svejgaard

Section of Forensic Genetics

33 Citations (Scopus)

Abstract

The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.

Original language	English
Journal	Journal of Neuroimmunology
Volume	27
Issue number	1
Pages (from-to)	85-8
Number of pages	3
ISSN	0165-5728
Publication status	Published - 1990

Cite this

@article{c27a55d0e4be11deba73000ea68e967b,

title = "Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis",

abstract = "The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.",

author = "L Fugger and N Morling and M Sandberg-Wollheim and Ryder, {L P} and A Svejgaard",

note = "Keywords: Adolescent; Adult; Alleles; Child; Genes; Humans; Multiple Sclerosis; Optic Neuritis; Phenotype; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Tumor Necrosis Factor-alpha",

year = "1990",

language = "English",

volume = "27",

pages = "85--8",

journal = "Journal of Neuroimmunology",

issn = "0165-5728",

publisher = "Elsevier",

number = "1",

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T1 - Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis

AU - Fugger, L

AU - Morling, N

AU - Sandberg-Wollheim, M

AU - Ryder, L P

AU - Svejgaard, A

N1 - Keywords: Adolescent; Adult; Alleles; Child; Genes; Humans; Multiple Sclerosis; Optic Neuritis; Phenotype; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Tumor Necrosis Factor-alpha

PY - 1990

Y1 - 1990

N2 - The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.

AB - The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.

M3 - Journal article

C2 - 1969423

SN - 0165-5728

VL - 27

SP - 85

EP - 88

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

IS - 1

ER -

Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis

Abstract

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