Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Huma Aftab; Dirk L. Christensen; Atiqa Ambreen; Mohammad Jamil; Peter Garred; Jørgen H. Petersen; Susanne D. Nielsen; Ib C. Bygbjerg

doi:10.4269/ajtmh.16-0816

Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Huma Aftab, Dirk L. Christensen, Atiqa Ambreen, Mohammad Jamil, Peter Garred, Jørgen H. Petersen, Susanne D. Nielsen, Ib C. Bygbjerg

6 Citations (Scopus)

67 Downloads (Pure)

Abstract

Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.

Original language	English
Journal	American Journal of Tropical Medicine and Hygiene
Volume	97
Issue number	4
Pages (from-to)	1099-1102
Number of pages	4
ISSN	0002-9637
DOIs	https://doi.org/10.4269/ajtmh.16-0816
Publication status	Published - Oct 2017

Keywords

Adult
Aged
Aged, 80 and over
Antitubercular Agents
Diabetes Mellitus
Female
Humans
Hypoglycemic Agents
Male
Middle Aged
Pakistan
Prevalence
Tuberculosis
Journal Article

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?",

abstract = "Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.",

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T2 - Is It Reversible after Complete Treatment?

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AU - Ambreen, Atiqa

AU - Jamil, Mohammad

AU - Garred, Peter

AU - Petersen, Jørgen H.

AU - Nielsen, Susanne D.

AU - Bygbjerg, Ib C.

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AB - Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.

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Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Abstract

Keywords

UN SDGs

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