Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Huma Aftab; Dirk L. Christensen; Atiqa Ambreen; Mohammad Jamil; Peter Garred; Jørgen H. Petersen; Susanne D. Nielsen; Ib C. Bygbjerg

doi:10.4269/ajtmh.16-0816

Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Huma Aftab, Dirk L. Christensen, Atiqa Ambreen, Mohammad Jamil, Peter Garred, Jørgen H. Petersen, Susanne D. Nielsen, Ib C. Bygbjerg

6 Citationer (Scopus)

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Abstract

Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.

Originalsprog	Engelsk
Tidsskrift	American Journal of Tropical Medicine and Hygiene
Vol/bind	97
Udgave nummer	4
Sider (fra-til)	1099-1102
Antal sider	4
ISSN	0002-9637
DOI	https://doi.org/10.4269/ajtmh.16-0816
Status	Udgivet - okt. 2017

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Citationsformater

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title = "Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?",

abstract = "Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.",

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T2 - Is It Reversible after Complete Treatment?

AU - Aftab, Huma

AU - Christensen, Dirk L.

AU - Ambreen, Atiqa

AU - Jamil, Mohammad

AU - Garred, Peter

AU - Petersen, Jørgen H.

AU - Nielsen, Susanne D.

AU - Bygbjerg, Ib C.

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AB - Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.

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KW - Aged, 80 and over

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Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?

Abstract

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