Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

TY - JOUR

T1 - Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

AU - Sato, Shogo

AU - Basse, Astrid Linde

AU - Schönke, Milena

AU - Chen, Siwei

AU - Samad, Muntaha

AU - Altıntaş, Ali

AU - Laker, Rhianna C

AU - Dalbram, Emilie

AU - Barrès, Romain

AU - Baldi, Pierre

AU - Treebak, Jonas T.

AU - Zierath, Juleen R

AU - Sassone-Corsi, Paolo

PY - 2019/7/2

Y1 - 2019/7/2

N2 - Sato and colleagues investigate time-dependent impact of exercise on skeletal muscle, revealing altered daily metabolic cycles after exercise specific to the time of day. Exercise at the early active phase robustly activates the HIF1α pathway, followed by glycolytic activation, usage of alternative fuels, and adaptation of systemic energy expenditure.

AB - Sato and colleagues investigate time-dependent impact of exercise on skeletal muscle, revealing altered daily metabolic cycles after exercise specific to the time of day. Exercise at the early active phase robustly activates the HIF1α pathway, followed by glycolytic activation, usage of alternative fuels, and adaptation of systemic energy expenditure.

U2 - 10.1016/j.cmet.2019.03.013

DO - 10.1016/j.cmet.2019.03.013

M3 - Journal article

C2 - 31006592

SN - 1550-4131

VL - 30

SP - 92-110.e4

JO - Cell Metabolism

JF - Cell Metabolism

IS - 1

ER -