[Thrombotic microangiopathies]

O.J. Nielsen; L. Friis-Hansen

[Thrombotic microangiopathies]

Abstract

The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiological defect in most cases of thrombotic microangiopathic diseases. Early recognition and a secure distinction from other conditions that resemble TMA diseases is essential in order to institute adequate treatment and to obtain a favourable outcome in terms of both survival and development of serious sequelae
Udgivelsesdato: 2009/11/30

Original language	Danish
Journal	Ugeskrift for læger
Volume	171
Issue number	49
Pages (from-to)	3614-3620
Number of pages	6
ISSN	0041-5782
Publication status	Published - 2009

Cite this

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title = "[Thrombotic microangiopathies]",

abstract = "The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiological defect in most cases of thrombotic microangiopathic diseases. Early recognition and a secure distinction from other conditions that resemble TMA diseases is essential in order to institute adequate treatment and to obtain a favourable outcome in terms of both survival and development of serious sequelae Udgivelsesdato: 2009/11/30",

author = "O.J. Nielsen and L. Friis-Hansen",

note = "Cochrane: Den danske tekst klippet hertil, De trombotiske mikroangiopatier, og den engelske tekst downloadet.",

year = "2009",

language = "Dansk",

volume = "171",

pages = "3614--3620",

journal = "Ugeskrift for Laeger",

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number = "49",

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T1 - [Thrombotic microangiopathies]

AU - Nielsen, O.J.

AU - Friis-Hansen, L.

N1 - Cochrane: Den danske tekst klippet hertil, De trombotiske mikroangiopatier, og den engelske tekst downloadet.

PY - 2009

Y1 - 2009

N2 - The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiological defect in most cases of thrombotic microangiopathic diseases. Early recognition and a secure distinction from other conditions that resemble TMA diseases is essential in order to institute adequate treatment and to obtain a favourable outcome in terms of both survival and development of serious sequelae Udgivelsesdato: 2009/11/30

AB - The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiological defect in most cases of thrombotic microangiopathic diseases. Early recognition and a secure distinction from other conditions that resemble TMA diseases is essential in order to institute adequate treatment and to obtain a favourable outcome in terms of both survival and development of serious sequelae Udgivelsesdato: 2009/11/30

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 171

SP - 3614

EP - 3620

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 49

ER -