The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

Maria Faurholt-Jepsen; Daniel Faurholt-Jepsen; N Range; G Praygod; K Jeremiah; M G Aabye; J Changalucha; H Krarup; Dirk Lund Christensen; A B Andersen; Søren Brage; Henrik Friis

doi:10.1017/s0950268813002070

The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

Maria Faurholt-Jepsen, Daniel Faurholt-Jepsen, N Range, G Praygod, K Jeremiah, M G Aabye, J Changalucha, H Krarup, Dirk Lund Christensen, A B Andersen, Søren Brage, Henrik Friis

3 Citations (Scopus)

Abstract

We assessed the role of tuberculosis (TB) disease and HIV infection on the level of physical activity. A combined heart rate and movement sensor was used to assess habitual physical activity in TB patients and non-TB controls. The association between sputum-negative TB, sputum-positive TB, HIV and physical activity estimates were assessed in multivariable linear regression models adjusted for age, sex, haemoglobin and alpha-1-Acid glycoprotein (AGP). Sputum-positive [e^B 0·43, 95% confidence interval (CI) 0·29-0·64] and sputum-negative (e^B 0·67, 95% CI 0·47-0·94) TB as well as HIV infection (e^B 0·59, 95% CI 0·46-0·75) were associated with reduced activity compared to controls. Anaemia accounted for a substantial part of the effects of HIV, while elevated AGP primarily mediated the TB effect. The level of physical activity is highly influenced by TB and HIV, and mainly mediated through anaemia of infection and associated with elevated acute phase response.

Original language	English
Journal	Epidemiology and Infection
Volume	142
Issue number	6
Pages (from-to)	1334-1342
Number of pages	9
ISSN	0950-2688
DOIs	https://doi.org/10.1017/s0950268813002070
Publication status	Published - Jun 2014

Keywords

Accelerometry
Adult
Female
Heart Rate
Humans
Male
Monitoring, Physiologic
Motor Activity
Tanzania
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1017/s0950268813002070

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/BD49CA6BB066CCF370E0238F14C25CCC/S0950268813002070a.pdf/div-class-title-the-use-of-combined-heart-rate-response-and-accelerometry-to-assess-the-level-and-predictors-of-physical-activity-in-tuberculosis-patients-in-tanzania-div.pdf

Cite this

Faurholt-Jepsen, M., Faurholt-Jepsen, D., Range, N., Praygod, G., Jeremiah, K., Aabye, M. G., Changalucha, J., Krarup, H., Christensen, D. L., Andersen, A. B., Brage, S., & Friis, H. (2014). The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania. Epidemiology and Infection, 142(6), 1334-1342. https://doi.org/10.1017/s0950268813002070

The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania. / Faurholt-Jepsen, Maria; Faurholt-Jepsen, Daniel; Range, N et al.
In: Epidemiology and Infection, Vol. 142, No. 6, 06.2014, p. 1334-1342.

Research output: Contribution to journal › Journal article › Research › peer-review

Faurholt-Jepsen, M, Faurholt-Jepsen, D, Range, N, Praygod, G, Jeremiah, K, Aabye, MG, Changalucha, J, Krarup, H, Christensen, DL, Andersen, AB, Brage, S & Friis, H 2014, 'The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania', Epidemiology and Infection, vol. 142, no. 6, pp. 1334-1342. https://doi.org/10.1017/s0950268813002070

@article{9fdd283fb51d477a847427c9819582d5,

title = "The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania",

abstract = "We assessed the role of tuberculosis (TB) disease and HIV infection on the level of physical activity. A combined heart rate and movement sensor was used to assess habitual physical activity in TB patients and non-TB controls. The association between sputum-negative TB, sputum-positive TB, HIV and physical activity estimates were assessed in multivariable linear regression models adjusted for age, sex, haemoglobin and alpha-1-Acid glycoprotein (AGP). Sputum-positive [eB 0·43, 95% confidence interval (CI) 0·29-0·64] and sputum-negative (eB 0·67, 95% CI 0·47-0·94) TB as well as HIV infection (eB 0·59, 95% CI 0·46-0·75) were associated with reduced activity compared to controls. Anaemia accounted for a substantial part of the effects of HIV, while elevated AGP primarily mediated the TB effect. The level of physical activity is highly influenced by TB and HIV, and mainly mediated through anaemia of infection and associated with elevated acute phase response.",

keywords = "Accelerometry, Adult, Female, Heart Rate, Humans, Male, Monitoring, Physiologic, Motor Activity, Tanzania, Tuberculosis",

author = "Maria Faurholt-Jepsen and Daniel Faurholt-Jepsen and N Range and G Praygod and K Jeremiah and Aabye, {M G} and J Changalucha and H Krarup and Christensen, {Dirk Lund} and Andersen, {A B} and S{\o}ren Brage and Henrik Friis",

note = "CURIS 2014 NEXS 218",

year = "2014",

month = jun,

doi = "10.1017/s0950268813002070",

language = "English",

volume = "142",

pages = "1334--1342",

journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

number = "6",

}

TY - JOUR

T1 - The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

AU - Faurholt-Jepsen, Maria

AU - Faurholt-Jepsen, Daniel

AU - Range, N

AU - Praygod, G

AU - Jeremiah, K

AU - Aabye, M G

AU - Changalucha, J

AU - Krarup, H

AU - Christensen, Dirk Lund

AU - Andersen, A B

AU - Brage, Søren

AU - Friis, Henrik

N1 - CURIS 2014 NEXS 218

PY - 2014/6

Y1 - 2014/6

N2 - We assessed the role of tuberculosis (TB) disease and HIV infection on the level of physical activity. A combined heart rate and movement sensor was used to assess habitual physical activity in TB patients and non-TB controls. The association between sputum-negative TB, sputum-positive TB, HIV and physical activity estimates were assessed in multivariable linear regression models adjusted for age, sex, haemoglobin and alpha-1-Acid glycoprotein (AGP). Sputum-positive [eB 0·43, 95% confidence interval (CI) 0·29-0·64] and sputum-negative (eB 0·67, 95% CI 0·47-0·94) TB as well as HIV infection (eB 0·59, 95% CI 0·46-0·75) were associated with reduced activity compared to controls. Anaemia accounted for a substantial part of the effects of HIV, while elevated AGP primarily mediated the TB effect. The level of physical activity is highly influenced by TB and HIV, and mainly mediated through anaemia of infection and associated with elevated acute phase response.

AB - We assessed the role of tuberculosis (TB) disease and HIV infection on the level of physical activity. A combined heart rate and movement sensor was used to assess habitual physical activity in TB patients and non-TB controls. The association between sputum-negative TB, sputum-positive TB, HIV and physical activity estimates were assessed in multivariable linear regression models adjusted for age, sex, haemoglobin and alpha-1-Acid glycoprotein (AGP). Sputum-positive [eB 0·43, 95% confidence interval (CI) 0·29-0·64] and sputum-negative (eB 0·67, 95% CI 0·47-0·94) TB as well as HIV infection (eB 0·59, 95% CI 0·46-0·75) were associated with reduced activity compared to controls. Anaemia accounted for a substantial part of the effects of HIV, while elevated AGP primarily mediated the TB effect. The level of physical activity is highly influenced by TB and HIV, and mainly mediated through anaemia of infection and associated with elevated acute phase response.

KW - Accelerometry

KW - Adult

KW - Female

KW - Heart Rate

KW - Humans

KW - Male

KW - Monitoring, Physiologic

KW - Motor Activity

KW - Tanzania

KW - Tuberculosis

U2 - 10.1017/s0950268813002070

DO - 10.1017/s0950268813002070

M3 - Journal article

C2 - 24007696

SN - 0950-2688

VL - 142

SP - 1334

EP - 1342

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 6

ER -

The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this