Keyphrases
Binding Core
100%
GluR2
100%
Ligand Binding
100%
Glutamate
100%
MGluR3
37%
Methyl
37%
Propionate
25%
GluR1
25%
2-amino-3
25%
Ionotropic Receptor
25%
Competitive Antagonist
12%
Receptor Subtypes
12%
High Affinity
12%
3-dione
12%
Central Nervous System
12%
Steric Hindrance
12%
Binding Cleft
12%
Brain Disorders
12%
Binding Mode
12%
Endogenous Ligand
12%
Brain Function
12%
Protomers
12%
Normal Brain
12%
MGluR4
12%
In Vitro Assay
12%
Novel Class
12%
Binding Affinity
12%
Isothermal Titration Calorimetry
12%
Receptor Binding
12%
Epileptic Seizure
12%
Ligand-binding Domain
12%
Hydrogen Bonds (H-bonds)
12%
Neuroprotective Effect
12%
Receptor Selectivity
12%
Open Conformation
12%
X-ray Structure
12%
2D Domain
12%
Synaptic Transmission
12%
Oxime
12%
Phenyl
12%
Apo Structure
12%
Anticonvulsant
12%
Pyrrol
12%
Neuroscience
Ligand Binding
100%
Glutamic Acid
100%
Receptor
66%
Propionate
33%
Propionic Acid
33%
Glutamate Receptor
33%
Binding Affinity
16%
Gamma-Hydroxybutyric Acid
16%
Oxime
16%
Receptor Subtype
16%
Isoquinoline
16%
Cleft
16%
Brain Disease
16%
Anticonvulsant
16%
Receptor Binding
16%
Central Nervous System
16%
Epileptic Seizure
16%
DNQX
16%
Calorimetry
16%
Brain Function
16%
Synaptic Transmission
16%
Neuroprotective Agent
16%
In Vitro
16%
Pharmacology, Toxicology and Pharmaceutical Science
Dimer
100%
2 [5 (4 Dimethylsulfamoylphenyl) 6,7,8,9 Tetrahydro 8 Methyl 2 Oxo 1h pyrrolo[3,2 H]isoquinolin 3 Yliminoxy] 4 Hydroxybutyric Acid
100%
Glutamic Acid
100%
Receptor
62%
Propionic Acid
25%
Glutamate Receptor
25%
Calorimetry
12%
Receptor Subtype
12%
6,7 Dinitro 2,3 Quinoxalinedione
12%
Competitive Antagonist
12%
Anticonvulsive Agent
12%
Seizure
12%
Isoquinoline
12%
Neuroprotective Agent
12%
Gamma-Hydroxybutyric Acid
12%
Brain Disease
12%
Oxime
12%
Biochemistry, Genetics and Molecular Biology
Glutamic Acid
100%
Ligand Binding
100%
Glutamate Receptor
33%
Protomer
16%
Receptor Binding
16%
Enthalpy
16%
Isothermal Titration Calorimetry
16%
Brain Function
16%
Conformation
16%
Binding Affinity
16%
Stereospecificity
16%
X Ray
16%
Synaptic Transmission
16%
Gamma-Hydroxybutyric Acid
16%
Binding Domain
16%