The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

TY - JOUR

T1 - The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

AU - Ba-Ali, Shakoor

AU - Jensen, Rigmor Højland

AU - Larsen, Line Sofie

AU - Lund-Andersen, Henrik

AU - Hamann, Steffen

PY - 2018/3/4

Y1 - 2018/3/4

N2 - Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).

AB - Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).

KW - IIH

KW - ipRGCs

KW - melanopsin

KW - PIPR

KW - pupillary light reflex

KW - pupillometry

U2 - 10.1080/01658107.2017.1344251

DO - 10.1080/01658107.2017.1344251

M3 - Journal article

C2 - 29563950

AN - SCOPUS:85027855404

SN - 0165-8107

VL - 42

SP - 65

EP - 72

JO - Neuro-Ophthalmology

JF - Neuro-Ophthalmology

IS - 2

ER -