The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

Shakoor Ba-Ali; Rigmor Højland Jensen; Line Sofie Larsen; Henrik Lund-Andersen; Steffen Hamann

doi:10.1080/01658107.2017.1344251

The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

Shakoor Ba-Ali^*, Rigmor Højland Jensen, Line Sofie Larsen, Henrik Lund-Andersen, Steffen Hamann

^*Corresponding author af dette arbejde

Institut for Klinisk Medicin

1 Citationer (Scopus)

Abstract

Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).

Originalsprog	Engelsk
Tidsskrift	Neuro-Ophthalmology
Vol/bind	42
Udgave nummer	2
Sider (fra-til)	65–72
ISSN	0165-8107
DOI	https://doi.org/10.1080/01658107.2017.1344251
Status	Udgivet - 4 mar. 2018

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10.1080/01658107.2017.1344251

Citationsformater

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title = "The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension",

abstract = "Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).",

keywords = "IIH, ipRGCs, melanopsin, PIPR, pupillary light reflex, pupillometry",

author = "Shakoor Ba-Ali and Jensen, {Rigmor H{\o}jland} and Larsen, {Line Sofie} and Henrik Lund-Andersen and Steffen Hamann",

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doi = "10.1080/01658107.2017.1344251",

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T1 - The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

AU - Ba-Ali, Shakoor

AU - Jensen, Rigmor Højland

AU - Larsen, Line Sofie

AU - Lund-Andersen, Henrik

AU - Hamann, Steffen

PY - 2018/3/4

Y1 - 2018/3/4

N2 - Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).

AB - Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH (n = 13), the authors found no significant difference in the melanopsin-mediated PLR (p = 0.48).

KW - IIH

KW - ipRGCs

KW - melanopsin

KW - PIPR

KW - pupillary light reflex

KW - pupillometry

U2 - 10.1080/01658107.2017.1344251

DO - 10.1080/01658107.2017.1344251

M3 - Journal article

C2 - 29563950

AN - SCOPUS:85027855404

SN - 0165-8107

VL - 42

SP - 65

EP - 72

JO - Neuro-Ophthalmology

JF - Neuro-Ophthalmology

IS - 2

ER -

The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

Abstract

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