The G protein-coupled receptor subset of the rat genome

TY - JOUR

T1 - The G protein-coupled receptor subset of the rat genome

AU - Gloriam, David E.

AU - Fredriksson, Robert

AU - Schiöth, Helgi B

PY - 2007

Y1 - 2007

N2 - The superfamily of G protein-coupled receptors (GPCRs) is one of the largest within most mammals. GPCRs are important targets for pharmaceuticals and the rat is one of the most widely used model organisms in biological research. Accurate comparisons of protein families in rat, mice and human are thus important for interpretation of many physiological and pharmacological studies. However, current automated protein predictions and annotations are limited and error prone.

AB - The superfamily of G protein-coupled receptors (GPCRs) is one of the largest within most mammals. GPCRs are important targets for pharmaceuticals and the rat is one of the most widely used model organisms in biological research. Accurate comparisons of protein families in rat, mice and human are thus important for interpretation of many physiological and pharmacological studies. However, current automated protein predictions and annotations are limited and error prone.

U2 - 10.1186/1471-2164-8-338

DO - 10.1186/1471-2164-8-338

M3 - Journal article

C2 - 17892602

SN - 1471-2164

VL - 8

SP - 338

JO - BMC Genomics

JF - BMC Genomics

ER -