The G protein-coupled receptor subset of the rat genome

David E. Gloriam; Robert Fredriksson; Helgi B Schiöth

doi:10.1186/1471-2164-8-338

The G protein-coupled receptor subset of the rat genome

David E. Gloriam, Robert Fredriksson, Helgi B Schiöth

153 Citationer (Scopus)

Abstract

The superfamily of G protein-coupled receptors (GPCRs) is one of the largest within most mammals. GPCRs are important targets for pharmaceuticals and the rat is one of the most widely used model organisms in biological research. Accurate comparisons of protein families in rat, mice and human are thus important for interpretation of many physiological and pharmacological studies. However, current automated protein predictions and annotations are limited and error prone.

Originalsprog	Engelsk
Tidsskrift	B M C Genomics
Vol/bind	8
Sider (fra-til)	338
ISSN	1471-2164
DOI	https://doi.org/10.1186/1471-2164-8-338
Status	Udgivet - 2007
Udgivet eksternt	Ja

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10.1186/1471-2164-8-338

Citationsformater

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AU - Gloriam, David E.

AU - Fredriksson, Robert

AU - Schiöth, Helgi B

PY - 2007

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N2 - The superfamily of G protein-coupled receptors (GPCRs) is one of the largest within most mammals. GPCRs are important targets for pharmaceuticals and the rat is one of the most widely used model organisms in biological research. Accurate comparisons of protein families in rat, mice and human are thus important for interpretation of many physiological and pharmacological studies. However, current automated protein predictions and annotations are limited and error prone.

AB - The superfamily of G protein-coupled receptors (GPCRs) is one of the largest within most mammals. GPCRs are important targets for pharmaceuticals and the rat is one of the most widely used model organisms in biological research. Accurate comparisons of protein families in rat, mice and human are thus important for interpretation of many physiological and pharmacological studies. However, current automated protein predictions and annotations are limited and error prone.

U2 - 10.1186/1471-2164-8-338

DO - 10.1186/1471-2164-8-338

M3 - Journal article

C2 - 17892602

SN - 1471-2164

VL - 8

SP - 338

JO - BMC Genomics

JF - BMC Genomics

ER -

The G protein-coupled receptor subset of the rat genome

Abstract

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