The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

P. Magnussen; A. Yakubu; P. Bloch

The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

P. Magnussen^*, A. Yakubu, P. Bloch

^*Corresponding author for this work

DRUGS team

7 Citations (Scopus)

Abstract

A randomized, single-blind, controlled study comparing the efficacy of an ointment containing two antibiotics, one containing one antibiotic plus hydrocortisone, and no treatment in reducing secondary infections in patients with patent Guinea worm was undertaken in the northern region of Ghana. Seventy seven patients were included. Time to complete healing was significantly shorter in the treatment groups compared with the controls (P = 0.044 and P = 0.003, respectively). Secondary infections occurred more often in the controls (P = 0.00014). Ointments containing antibiotics are recommended for application at the early stage of patent Guinea worm infection.

Original language	English
Journal	American Journal of Tropical Medicine and Hygiene
Volume	51
Issue number	6
Pages (from-to)	797-799
Number of pages	3
ISSN	0002-9637
Publication status	Published - 1 Dec 1994

Cite this

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AB - A randomized, single-blind, controlled study comparing the efficacy of an ointment containing two antibiotics, one containing one antibiotic plus hydrocortisone, and no treatment in reducing secondary infections in patients with patent Guinea worm was undertaken in the northern region of Ghana. Seventy seven patients were included. Time to complete healing was significantly shorter in the treatment groups compared with the controls (P = 0.044 and P = 0.003, respectively). Secondary infections occurred more often in the controls (P = 0.00014). Ointments containing antibiotics are recommended for application at the early stage of patent Guinea worm infection.

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The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

Abstract

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