The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

TY - JOUR

T1 - The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

AU - Magnussen, P.

AU - Yakubu, A.

AU - Bloch, P.

PY - 1994/12/1

Y1 - 1994/12/1

N2 - A randomized, single-blind, controlled study comparing the efficacy of an ointment containing two antibiotics, one containing one antibiotic plus hydrocortisone, and no treatment in reducing secondary infections in patients with patent Guinea worm was undertaken in the northern region of Ghana. Seventy seven patients were included. Time to complete healing was significantly shorter in the treatment groups compared with the controls (P = 0.044 and P = 0.003, respectively). Secondary infections occurred more often in the controls (P = 0.00014). Ointments containing antibiotics are recommended for application at the early stage of patent Guinea worm infection.

AB - A randomized, single-blind, controlled study comparing the efficacy of an ointment containing two antibiotics, one containing one antibiotic plus hydrocortisone, and no treatment in reducing secondary infections in patients with patent Guinea worm was undertaken in the northern region of Ghana. Seventy seven patients were included. Time to complete healing was significantly shorter in the treatment groups compared with the controls (P = 0.044 and P = 0.003, respectively). Secondary infections occurred more often in the controls (P = 0.00014). Ointments containing antibiotics are recommended for application at the early stage of patent Guinea worm infection.

UR - http://www.scopus.com/inward/record.url?scp=0028557045&partnerID=8YFLogxK

M3 - Journal article

C2 - 7810814

AN - SCOPUS:0028557045

SN - 0002-9637

VL - 51

SP - 797

EP - 799

JO - Journal. National Malaria Society

JF - Journal. National Malaria Society

IS - 6

ER -