Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

Elina T. L'Estrade; Hanne D. Hansen; Christina Falk-Petersen; Anne Haugaard; Nane Griem-Krey; Sascha Jung; Hartmut Lueddens; Tanja Schirmeister; Maria Erlandsson; Tomas Ohlsson; Gitte M. Knudsen; Matthias M. Herth; Petrine Wellendorph; Bente Frolund

doi:10.1021/acsomega.9b00434

Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

Elina T. L'Estrade, Hanne D. Hansen, Christina Falk-Petersen, Anne Haugaard, Nane Griem-Krey, Sascha Jung, Hartmut Lueddens, Tanja Schirmeister, Maria Erlandsson, Tomas Ohlsson, Gitte M. Knudsen, Matthias M. Herth, Petrine Wellendorph, Bente Frolund

4 Citations (Scopus)

15 Downloads (Pure)

Original language	English
Journal	ACS Omega
Volume	4
Issue number	5
Pages (from-to)	8846-8851
ISSN	2470-1343
DOIs	https://doi.org/10.1021/acsomega.9b00434
Publication status	Published - 31 May 2019

Access to Document

10.1021/acsomega.9b00434Licence: CC BY-NC

acsomega.9b00434Final published version, 1.2 MBLicence: CC BY-NC

Fingerprint

Dive into the research topics of 'Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors'. Together they form a unique fingerprint.

Cite this

L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, N., Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, G. M., Herth, M. M., Wellendorph, P., & Frolund, B. (2019). Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors. ACS Omega, 4(5), 8846-8851. https://doi.org/10.1021/acsomega.9b00434

Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors. / L'Estrade, Elina T.; Hansen, Hanne D.; Falk-Petersen, Christina et al.

In: ACS Omega, Vol. 4, No. 5, 31.05.2019, p. 8846-8851.

Research output: Contribution to journal › Journal article › Research › peer-review

L'Estrade, ET, Hansen, HD, Falk-Petersen, C, Haugaard, A, Griem-Krey, N, Jung, S, Lueddens, H, Schirmeister, T, Erlandsson, M, Ohlsson, T, Knudsen, GM , Herth, MM , Wellendorph, P & Frolund, B 2019, 'Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors', ACS Omega, vol. 4, no. 5, pp. 8846-8851. https://doi.org/10.1021/acsomega.9b00434

L'Estrade ET, Hansen HD, Falk-Petersen C, Haugaard A, Griem-Krey N, Jung S et al. Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors. ACS Omega. 2019 May 31;4(5):8846-8851. doi: 10.1021/acsomega.9b00434

@article{bf583b78d2d441419fe664a5e59809e0,

title = "Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors",

author = "L'Estrade, {Elina T.} and Hansen, {Hanne D.} and Christina Falk-Petersen and Anne Haugaard and Nane Griem-Krey and Sascha Jung and Hartmut Lueddens and Tanja Schirmeister and Maria Erlandsson and Tomas Ohlsson and Knudsen, {Gitte M.} and Herth, {Matthias M.} and Petrine Wellendorph and Bente Frolund",

year = "2019",

month = may,

day = "31",

doi = "10.1021/acsomega.9b00434",

language = "English",

volume = "4",

pages = "8846--8851",

journal = "ACS Omega",

issn = "2470-1343",

publisher = "ACS Publications",

number = "5",

}

TY - JOUR

T1 - Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

AU - L'Estrade, Elina T.

AU - Hansen, Hanne D.

AU - Falk-Petersen, Christina

AU - Haugaard, Anne

AU - Griem-Krey, Nane

AU - Jung, Sascha

AU - Lueddens, Hartmut

AU - Schirmeister, Tanja

AU - Erlandsson, Maria

AU - Ohlsson, Tomas

AU - Knudsen, Gitte M.

AU - Herth, Matthias M.

AU - Wellendorph, Petrine

AU - Frolund, Bente

PY - 2019/5/31

Y1 - 2019/5/31

U2 - 10.1021/acsomega.9b00434

DO - 10.1021/acsomega.9b00434

M3 - Journal article

C2 - 31459972

SN - 2470-1343

VL - 4

SP - 8846

EP - 8851

JO - ACS Omega

JF - ACS Omega

IS - 5

ER -