Research output per year
Research output per year
Personal profile
Short presentation
My research is focused on the elucidation of the in vivo mechanism-of-action of GHB ligands. GHB (g-hydroxybutyric acid) is a proposed neuromodulator, but it is also known as the drug of abuse Fantasy and the clinically prescribed drug Xyrem for the treatment of narcolepsy. Pre-clinical studies showed a neuroprotective effect of GHB ligands in acute brain injury. Therefore, my project is focussing studying the neuroprotective potential of GHB ligands by employing the model of photothrombotic stroke.
CV
Academic degrees
2018: MSc in Pharmaceutical Science, University of Copenhagen.
2016: BSc in Life Science, Leibniz University (Hanover, Germany).
Employments
2018: Research assistent at Experimental Pharmacology, Deparment of Drug Design and Pharmacology, University of Copenhagen.
Education/Academic qualification
University of Copenhagen
Award Date: 31 Aug 2018
Leibniz University Hannover
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Research output
- 2 Journal article
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Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets
Griem-Krey, N., Klein, A. B., Herth, M. & Wellendorph, P., 12 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 11 p., e58879.Research output: Contribution to journal › Journal article › Communication
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Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors
L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, N., Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, G. M., Herth, M. M., Wellendorph, P. & Frolund, B., 31 May 2019, In: ACS Omega. 4, 5, p. 8846-8851Research output: Contribution to journal › Journal article › Research › peer-review