Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach

Lene Petersen; Per T. Jørgensen; Claus Nielsen; Thomas Hesselhøj Hansen; John Nielsen; Erik B. Pedersen

doi:10.1021/jm040845b

Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach

Lene Petersen, Per T. Jørgensen, Claus Nielsen, Thomas Hesselhøj Hansen, John Nielsen, Erik B. Pedersen

24 Citations (Scopus)

Original language	English
Journal	Journal of Medicinal Chemistry
Pages (from-to)	1211-1220
Number of pages	10
ISSN	0022-2623
DOIs	https://doi.org/10.1021/jm040845b
Publication status	Published - 2005

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10.1021/jm040845b

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Petersen, L., Jørgensen, P. T., Nielsen, C., Hansen, T. H., Nielsen, J., & Pedersen, E. B. (2005). Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach. Journal of Medicinal Chemistry, 1211-1220. https://doi.org/10.1021/jm040845b

Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach. / Petersen, Lene; Jørgensen, Per T.; Nielsen, Claus et al.
In: Journal of Medicinal Chemistry, 2005, p. 1211-1220.

Research output: Contribution to journal › Journal article › Research › peer-review

Petersen, L, Jørgensen, PT, Nielsen, C, Hansen, TH , Nielsen, J & Pedersen, EB 2005, 'Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach', Journal of Medicinal Chemistry, pp. 1211-1220. https://doi.org/10.1021/jm040845b

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