Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach

Lene Petersen; Per T. Jørgensen; Claus Nielsen; Thomas Hesselhøj Hansen; John Nielsen; Erik B. Pedersen

doi:10.1021/jm040845b

Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach

Lene Petersen, Per T. Jørgensen, Claus Nielsen, Thomas Hesselhøj Hansen, John Nielsen, Erik B. Pedersen

24 Citations (Scopus)

Original language	English
Journal	Journal of Medicinal Chemistry
Pages (from-to)	1211-1220
Number of pages	10
ISSN	0022-2623
DOIs	https://doi.org/10.1021/jm040845b
Publication status	Published - 2005

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/jm040845b

Cite this

Petersen, L., Jørgensen, P. T., Nielsen, C., Hansen, T. H., Nielsen, J., & Pedersen, E. B. (2005). Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach. Journal of Medicinal Chemistry, 1211-1220. https://doi.org/10.1021/jm040845b

Synthesis and evaluation of double-prodrugs against HIV : Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach. / Petersen, Lene; Jørgensen, Per T.; Nielsen, Claus et al.

In: Journal of Medicinal Chemistry, 2005, p. 1211-1220.

Research output: Contribution to journal › Journal article › Research › peer-review

Petersen, L, Jørgensen, PT, Nielsen, C, Hansen, TH , Nielsen, J & Pedersen, EB 2005, 'Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach', Journal of Medicinal Chemistry, pp. 1211-1220. https://doi.org/10.1021/jm040845b

@article{8bb31de0a1bf11ddb6ae000ea68e967b,

title = "Synthesis and evaluation of double-prodrugs against HIV: Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach",

author = "Lene Petersen and J{\o}rgensen, {Per T.} and Claus Nielsen and Hansen, {Thomas Hesselh{\o}j} and John Nielsen and Pedersen, {Erik B.}",

year = "2005",

doi = "10.1021/jm040845b",

language = "English",

pages = "1211--1220",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

}

TY - JOUR

T1 - Synthesis and evaluation of double-prodrugs against HIV

T2 - Conjugation of D4T with 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach

AU - Petersen, Lene

AU - Jørgensen, Per T.

AU - Nielsen, Claus

AU - Hansen, Thomas Hesselhøj

AU - Nielsen, John

AU - Pedersen, Erik B.

PY - 2005

Y1 - 2005

U2 - 10.1021/jm040845b

DO - 10.1021/jm040845b

M3 - Journal article

C2 - 15715487

SN - 0022-2623

SP - 1211

EP - 1220

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -