Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Christina Gjerlev Poulsen; Morten Bestle; Lene Boesby

Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Translated title of the contribution: Successful treatment of severe dabigatran intoxication with idarucizumab in a patient with acute kidney injury

Christina Gjerlev Poulsen, Morten Bestle, Lene Boesby

Department of Clinical Medicine

Abstract

In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.

Translated title of the contribution	Successful treatment of severe dabigatran intoxication with idarucizumab in a patient with acute kidney injury
Original language	Danish
Article number	V08160562
Journal	Ugeskrift for Laeger
Volume	179
Issue number	7
Number of pages	3
ISSN	0041-5782
Publication status	Published - 1 Mar 2017

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Cite this

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title = "Succesfuld behandling af sv{\ae}r dabigatranoverdosering med idarucizumab hos en patient med nyresvigt",

abstract = "In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.",

author = "Poulsen, {Christina Gjerlev} and Morten Bestle and Lene Boesby",

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T1 - Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

AU - Poulsen, Christina Gjerlev

AU - Bestle, Morten

AU - Boesby, Lene

PY - 2017/3/1

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N2 - In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.

AB - In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.

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JO - Ugeskrift for Laeger

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ER -

Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Abstract

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