Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Christina Gjerlev Poulsen; Morten Bestle; Lene Boesby

Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Christina Gjerlev Poulsen, Morten Bestle, Lene Boesby

Institut for Klinisk Medicin

Abstract

In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.

Bidragets oversatte titel	Successful treatment of severe dabigatran intoxication with idarucizumab in a patient with acute kidney injury
Originalsprog	Dansk
Artikelnummer	V08160562
Tidsskrift	Ugeskrift for Laeger
Vol/bind	179
Udgave nummer	7
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 1 mar. 2017

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http://ugeskriftet.dk/videnskab/succesfuld-behandling-af-svaer-dabigatranoverdosering-med-idarucizumab-hos-en-patient-med

Citationsformater

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abstract = "In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.",

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AB - In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.

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Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

Abstract

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