Submikroskopiske kromosomanomalier som årsag til skizofreni

Thomas Hansen; Andrés Ingason; Thomas Werge

Submikroskopiske kromosomanomalier som årsag til skizofreni

Translated title of the contribution: Submicroscopic chromosomal anomalies as a cause of schizophrenia

Thomas Hansen, Andrés Ingason, Thomas Werge

Abstract

Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.

Translated title of the contribution	Submicroscopic chromosomal anomalies as a cause of schizophrenia
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	170
Issue number	46
Pages (from-to)	3773-6
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2008

Cite this

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title = "Submikroskopiske kromosomanomalier som {\aa}rsag til skizofreni",

abstract = "Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.",

author = "Thomas Hansen and Andr{\'e}s Ingason and Thomas Werge",

year = "2008",

language = "Dansk",

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T1 - Submikroskopiske kromosomanomalier som årsag til skizofreni

AU - Hansen, Thomas

AU - Ingason, Andrés

AU - Werge, Thomas

PY - 2008

Y1 - 2008

N2 - Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.

AB - Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 170

SP - 3773

EP - 3776

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 46

ER -

Submikroskopiske kromosomanomalier som årsag til skizofreni

Abstract

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