Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

TY - JOUR

T1 - Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

AU - Gjesing, A P

AU - Andersen, G

AU - Burgdorf, K S

AU - Borch-Johnsen, K

AU - Jørgensen, T

AU - Hansen, T

AU - Pedersen, O

PY - 2007/3

Y1 - 2007/3

N2 - Functional and common Arg16Gly and Gln27Glu polymorphisms have been identified in ADRB2, the gene encoding the beta2-adrenergic receptor. These variants have previously been examined for association with obesity, hypertension and diabetes with inconclusive results.

AB - Functional and common Arg16Gly and Gln27Glu polymorphisms have been identified in ADRB2, the gene encoding the beta2-adrenergic receptor. These variants have previously been examined for association with obesity, hypertension and diabetes with inconclusive results.

KW - Adult

KW - Amino Acid Substitution

KW - Body Mass Index

KW - Case-Control Studies

KW - Diabetes Mellitus, Type 2

KW - European Continental Ancestry Group

KW - Female

KW - Genetic Variation

KW - Humans

KW - Hypertension

KW - Middle Aged

KW - Obesity

KW - Polymerase Chain Reaction

KW - Polymorphism, Single Nucleotide

KW - Receptors, Adrenergic, beta-2

U2 - 10.1007/s00125-006-0578-8

DO - 10.1007/s00125-006-0578-8

M3 - Journal article

C2 - 17221209

SN - 0012-186X

VL - 50

SP - 563

EP - 568

JO - Diabetologia

JF - Diabetologia

IS - 3

ER -