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Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors
Jeppe A Olsen, Philip K Ahring,
Jette Sandholm Jensen Kastrup
,
Michael Gajhede
, Thomas Balle
26
Citations (Scopus)
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Medicine & Life Sciences
3-(3-(pyridine-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
100%
Nicotinic Receptors
51%
Cysteine Loop Ligand-Gated Ion Channel Receptors
32%
Binding Sites
21%
Lymnaea AChBP protein
19%
Benzodiazepines
18%
Aminobutyrates
13%
Cholinergic Agonists
12%
Drug Discovery
9%
Ion Channels
9%
X-Rays
7%
Pharmacology
6%
Chemical Compounds
Acetylcholine
49%
Agonist
33%
Benzodiazepine
26%
Binding Site
16%
Parasympathomimetic Agent
14%
Reaction Stoichiometry
9%
Drug
6%
Protein
4%
Ion
4%
Acid
4%