Solution conditions determine the relative importance of nucleation and growth processes in alpha-synuclein aggregation

Alexander K. Buell, Celine Galvagnion, Ricardo Gaspar, Emma Sparr, Michele Vendruscolo, Tuomas P. J. Knowles, Sara Linse, Christopher M. Dobson

308 Citations (Scopus)
Original languageEnglish
JournalProceedings of the National Academy of Sciences of the United States of America
Volume111
Issue number21
Pages (from-to)7671-7676
ISSN0027-8424
DOIs
Publication statusPublished - 27 May 2014
Externally publishedYes

Keywords

  • seeding
  • prion-like behavior
  • neurodegenerative disease
  • kinetic analysis
  • electrostatic interactions

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