Severe iron intoxication treated with exchange transfusion

Marcella Carlsson; Dina Cortes; Søren Jepsen; Thomas Kanstrup

doi:10.1136/adc.2007.123240

Severe iron intoxication treated with exchange transfusion

Marcella Carlsson, Dina Cortes, Søren Jepsen, Thomas Kanstrup

Department of Clinical Medicine

8 Citations (Scopus)

Abstract

An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

Original language	English
Journal	Archives of Disease in Childhood
Volume	93
Issue number	4
Pages (from-to)	321-2
Number of pages	2
ISSN	0003-9888
DOIs	https://doi.org/10.1136/adc.2007.123240
Publication status	Published - 2008

Keywords

Deferoxamine
Drug Therapy, Combination
Exchange Transfusion, Whole Blood
Female
Humans
Infant
Intensive Care
Iron
Siderophores

Access to Document

10.1136/adc.2007.123240

Cite this

@article{181b8b458f724703bcc3b9ebcd84d648,

title = "Severe iron intoxication treated with exchange transfusion",

abstract = "An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.",

keywords = "Deferoxamine, Drug Therapy, Combination, Exchange Transfusion, Whole Blood, Female, Humans, Infant, Intensive Care, Iron, Siderophores",

author = "Marcella Carlsson and Dina Cortes and S{\o}ren Jepsen and Thomas Kanstrup",

year = "2008",

doi = "10.1136/adc.2007.123240",

language = "English",

volume = "93",

pages = "321--2",

journal = "Archives of Disease in Childhood",

issn = "0003-9888",

publisher = "B M J Group",

number = "4",

}

TY - JOUR

T1 - Severe iron intoxication treated with exchange transfusion

AU - Carlsson, Marcella

AU - Cortes, Dina

AU - Jepsen, Søren

AU - Kanstrup, Thomas

PY - 2008

Y1 - 2008

N2 - An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

AB - An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

KW - Deferoxamine

KW - Drug Therapy, Combination

KW - Exchange Transfusion, Whole Blood

KW - Female

KW - Humans

KW - Infant

KW - Intensive Care

KW - Iron

KW - Siderophores

U2 - 10.1136/adc.2007.123240

DO - 10.1136/adc.2007.123240

M3 - Journal article

C2 - 18356385

SN - 0003-9888

VL - 93

SP - 321

EP - 322

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

IS - 4

ER -

Severe iron intoxication treated with exchange transfusion

Abstract

Keywords

Access to Document

Fingerprint

Cite this