Severe iron intoxication treated with exchange transfusion

Marcella Carlsson; Dina Cortes; Søren Jepsen; Thomas Kanstrup

doi:10.1136/adc.2007.123240

Severe iron intoxication treated with exchange transfusion

Marcella Carlsson, Dina Cortes, Søren Jepsen, Thomas Kanstrup

Institut for Klinisk Medicin

8 Citationer (Scopus)

Abstract

An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

Originalsprog	Engelsk
Tidsskrift	Archives of Disease in Childhood
Vol/bind	93
Udgave nummer	4
Sider (fra-til)	321-2
Antal sider	2
ISSN	0003-9888
DOI	https://doi.org/10.1136/adc.2007.123240
Status	Udgivet - 2008

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10.1136/adc.2007.123240

Citationsformater

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title = "Severe iron intoxication treated with exchange transfusion",

abstract = "An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.",

keywords = "Deferoxamine, Drug Therapy, Combination, Exchange Transfusion, Whole Blood, Female, Humans, Infant, Intensive Care, Iron, Siderophores",

author = "Marcella Carlsson and Dina Cortes and S{\o}ren Jepsen and Thomas Kanstrup",

year = "2008",

doi = "10.1136/adc.2007.123240",

language = "English",

volume = "93",

pages = "321--2",

journal = "Archives of Disease in Childhood",

issn = "0003-9888",

publisher = "B M J Group",

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TY - JOUR

T1 - Severe iron intoxication treated with exchange transfusion

AU - Carlsson, Marcella

AU - Cortes, Dina

AU - Jepsen, Søren

AU - Kanstrup, Thomas

PY - 2008

Y1 - 2008

N2 - An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

AB - An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

KW - Deferoxamine

KW - Drug Therapy, Combination

KW - Exchange Transfusion, Whole Blood

KW - Female

KW - Humans

KW - Infant

KW - Intensive Care

KW - Iron

KW - Siderophores

U2 - 10.1136/adc.2007.123240

DO - 10.1136/adc.2007.123240

M3 - Journal article

C2 - 18356385

SN - 0003-9888

VL - 93

SP - 321

EP - 322

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

IS - 4

ER -

Severe iron intoxication treated with exchange transfusion

Abstract

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