Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers

Gopal Raghunath Karemore; Sujatha Ukendt; Lavanya Rai; Keerhilatha Pai; V.B Kartha; Santhosh C

doi:10.1117/12.809930

Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers

Gopal Raghunath Karemore, Sujatha Ukendt, Lavanya Rai, Keerhilatha Pai, V.B Kartha, Santhosh C

Department of Computer Science

1 Citation (Scopus)

Abstract

The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.

Original language	English
Title of host publication	Proceedings of the SPIE : Biomolecular Imaging
Number of pages	9
Volume	7182
Publication date	2009
Pages	71820J-71820J-9
DOIs	https://doi.org/10.1117/12.809930
Publication status	Published - 2009
Event	SPIE-2009-Imaging, Manipulation of Biomolecules, Cells, and Tissues VII - California, United States Duration: 26 Jan 2009 → 28 Jan 2009

Conference

Conference	SPIE-2009-Imaging, Manipulation of Biomolecules, Cells, and Tissues VII
Country/Territory	United States
City	California
Period	26/01/2009 → 28/01/2009

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Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers. / Karemore, Gopal Raghunath; Ukendt, Sujatha; Rai, Lavanya et al.
Proceedings of the SPIE: Biomolecular Imaging. Vol. 7182 2009. p. 71820J-71820J-9.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Karemore, GR, Ukendt, S, Rai, L, Pai, K, Kartha, VB & C, S 2009, Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers. in Proceedings of the SPIE: Biomolecular Imaging. vol. 7182, pp. 71820J-71820J-9, SPIE-2009-Imaging, Manipulation of Biomolecules, Cells, and Tissues VII, California, United States, 26/01/2009. https://doi.org/10.1117/12.809930

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abstract = "The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.",

author = "Karemore, {Gopal Raghunath} and Sujatha Ukendt and Lavanya Rai and Keerhilatha Pai and V.B Kartha and Santhosh C",

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AB - The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.

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M3 - Article in proceedings

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BT - Proceedings of the SPIE

Y2 - 26 January 2009 through 28 January 2009

ER -

Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers

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Conference

UN SDGs

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