Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers

Gopal Raghunath Karemore, Sujatha Ukendt, Lavanya Rai, Keerhilatha Pai, V.B Kartha, Santhosh C

1 Citation (Scopus)

Abstract

The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.
Original languageEnglish
Title of host publicationProceedings of the SPIE : Biomolecular Imaging
Number of pages9
Volume7182
Publication date2009
Pages71820J-71820J-9
DOIs
Publication statusPublished - 2009
EventSPIE-2009-Imaging, Manipulation of Biomolecules, Cells, and Tissues VII - California, United States
Duration: 26 Jan 200928 Jan 2009

Conference

ConferenceSPIE-2009-Imaging, Manipulation of Biomolecules, Cells, and Tissues VII
Country/TerritoryUnited States
CityCalifornia
Period26/01/200928/01/2009

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