TY - JOUR
T1 - Sequence and comparative analysis of Leuconostoc dairy bacteriophages
AU - Kot, Witold Piotr
AU - Hansen, Lars H.
AU - Neve, Horst
AU - Hammer, Karin
AU - Jacobsen, Susanne
AU - Pedersen, Per D.
AU - Sørensen, Søren Johannes
AU - Heller, Knut J.
AU - Vogensen, Finn Kvist
N1 - Copyright © 2014 Elsevier B.V. All rights reserved.
PY - 2014/4/17
Y1 - 2014/4/17
N2 - Bacteriophages attacking Leuconostoc species may significantly influence the quality of the final product. There is however limited knowledge of this group of phages in the literature. We have determined the complete genome sequences of nine Leuconostoc bacteriophages virulent to either Leuconostoc mesenteroides or Leuconostoc pseudomesenteroides strains. The phages have dsDNA genomes with sizes ranging from 25.7 to 28.4kb. Comparative genomics analysis helped classify the 9 phages into two classes, which correlates with the host species. High percentage of similarity within the classes on both nucleotide and protein levels was observed. Genome comparison also revealed very high conservation of the overall genomic organization between the classes. The genes were organized in functional modules responsible for replication, packaging, head and tail morphogenesis, cell lysis and regulation and modification, respectively. No lysogeny modules were detected. To our knowledge this report provides the first comparative genomic work done on Leuconostoc dairy phages.
AB - Bacteriophages attacking Leuconostoc species may significantly influence the quality of the final product. There is however limited knowledge of this group of phages in the literature. We have determined the complete genome sequences of nine Leuconostoc bacteriophages virulent to either Leuconostoc mesenteroides or Leuconostoc pseudomesenteroides strains. The phages have dsDNA genomes with sizes ranging from 25.7 to 28.4kb. Comparative genomics analysis helped classify the 9 phages into two classes, which correlates with the host species. High percentage of similarity within the classes on both nucleotide and protein levels was observed. Genome comparison also revealed very high conservation of the overall genomic organization between the classes. The genes were organized in functional modules responsible for replication, packaging, head and tail morphogenesis, cell lysis and regulation and modification, respectively. No lysogeny modules were detected. To our knowledge this report provides the first comparative genomic work done on Leuconostoc dairy phages.
U2 - 10.1016/j.ijfoodmicro.2014.01.019
DO - 10.1016/j.ijfoodmicro.2014.01.019
M3 - Journal article
C2 - 24561391
SN - 0168-1605
VL - 176
SP - 29
EP - 37
JO - International Journal of Food Microbiology
JF - International Journal of Food Microbiology
ER -