Self-assembling drugs: A new therapeutic strategy

N. Hassan; Juan M. Ruso; Gonzalez Perez Alfredo

doi:10.1039/c0sm01529f

Self-assembling drugs: A new therapeutic strategy

N. Hassan, Juan M. Ruso, Gonzalez Perez Alfredo

11 Citations (Scopus)

Abstract

In the current work we proposed the new idea of "self-assembled drug" based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form worm-like micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo- electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.

Original language	English
Journal	Soft Matter
Volume	7
Issue number	11
Pages (from-to)	5194-5199
Number of pages	5
ISSN	1744-683X
DOIs	https://doi.org/10.1039/c0sm01529f
Publication status	Published - 7 Jun 2011

Access to Document

10.1039/c0sm01529f

Cite this

@article{b089fb6bd96741c1938de2eda0f5fd02,

title = "Self-assembling drugs: A new therapeutic strategy",

abstract = "In the current work we proposed the new idea of {"}self-assembled drug{"} based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form worm-like micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo- electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.",

author = "N. Hassan and Ruso, {Juan M.} and Alfredo, {Gonzalez Perez}",

year = "2011",

month = jun,

day = "7",

doi = "10.1039/c0sm01529f",

language = "English",

volume = "7",

pages = "5194--5199",

journal = "Journal of Materials Chemistry",

issn = "0959-9428",

publisher = "Royal Society of Chemistry",

number = "11",

}

TY - JOUR

T1 - Self-assembling drugs

T2 - A new therapeutic strategy

AU - Hassan, N.

AU - Ruso, Juan M.

AU - Alfredo, Gonzalez Perez

PY - 2011/6/7

Y1 - 2011/6/7

N2 - In the current work we proposed the new idea of "self-assembled drug" based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form worm-like micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo- electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.

AB - In the current work we proposed the new idea of "self-assembled drug" based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form worm-like micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo- electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.

U2 - 10.1039/c0sm01529f

DO - 10.1039/c0sm01529f

M3 - Journal article

SN - 0959-9428

VL - 7

SP - 5194

EP - 5199

JO - Journal of Materials Chemistry

JF - Journal of Materials Chemistry

IS - 11

ER -

Self-assembling drugs: A new therapeutic strategy

Abstract

Access to Document

Fingerprint

Cite this