Second generation sequencing of three STRs D3S1358, D12S391 and D21S11 in Danes and a new nomenclature for sequenced STR alleles

TY - JOUR

T1 - Second generation sequencing of three STRs D3S1358, D12S391 and D21S11 in Danes and a new nomenclature for sequenced STR alleles

AU - Gelardi, Chiara

AU - Rockenbauer, Eszter

AU - Dalsgaard, Sigrun

AU - Børsting, Claus

AU - Morling, Niels

N1 - Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

PY - 2014/9

Y1 - 2014/9

N2 - Second generation sequencing (SGS) may revolutionize the field of forensic STR typing. Two of the essential requirements for implementation of an SGS based approach for forensic investigations are (1) establishment of adequate frequency databases and (2) adoption of a new STR nomenclature. We report the STR sequences and allele frequencies of three STR loci: D3S1358, D12S391 and D21S11 in 197 unrelated Danes. We used a new STR nomenclature that depicts the locus name used in forensic genetics, the length of the repeat region divided by the repeat length (typically 4 nucleotides) and detailed sequence information of possible sub-repeats and SNPs within the amplified fragment.

AB - Second generation sequencing (SGS) may revolutionize the field of forensic STR typing. Two of the essential requirements for implementation of an SGS based approach for forensic investigations are (1) establishment of adequate frequency databases and (2) adoption of a new STR nomenclature. We report the STR sequences and allele frequencies of three STR loci: D3S1358, D12S391 and D21S11 in 197 unrelated Danes. We used a new STR nomenclature that depicts the locus name used in forensic genetics, the length of the repeat region divided by the repeat length (typically 4 nucleotides) and detailed sequence information of possible sub-repeats and SNPs within the amplified fragment.

U2 - 10.1016/j.fsigen.2014.04.016

DO - 10.1016/j.fsigen.2014.04.016

M3 - Journal article

C2 - 24893347

SN - 1872-4973

VL - 12

SP - 38

EP - 41

JO - Forensic Science International: Genetics

JF - Forensic Science International: Genetics

ER -