Role of gastrointestinal hormones in postprandial reduction of bone resorption

Dennis B Henriksen; Peter Alexandersen; Nina H Bjarnason; Tina Vilsbøll; Bolette Hartmann; Eva E G Henriksen; Inger Byrjalsen; Thure Krarup; Jens Juul Holst; Claus Christiansen

doi:http://dx.doi.org/10.1359/jbmr.2003.18.12.2180

Role of gastrointestinal hormones in postprandial reduction of bone resorption

Dennis B Henriksen, Peter Alexandersen, Nina H Bjarnason, Tina Vilsbøll, Bolette Hartmann, Eva E G Henriksen, Inger Byrjalsen, Thure Krarup, Jens Juul Holst, Claus Christiansen

229 Citations (Scopus)

Abstract

Collagen type I fragments, reflecting bone resorption, and release of gut hormones were investigated after a meal. Investigations led to a dose escalation study with glucagon like peptide-2 (GLP-2) in postmenopausal women. We found a dose-dependent effect of GLP-2 on the reduction of bone resorption.

Original language	English
Journal	J Bone Miner Res
Volume	18
Issue number	12
Pages (from-to)	2180-2190
Number of pages	10
DOIs	https://doi.org/10.1359/jbmr.2003.18.12.2180
Publication status	Published - 1 Dec 2003

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title = "Role of gastrointestinal hormones in postprandial reduction of bone resorption",

abstract = "Collagen type I fragments, reflecting bone resorption, and release of gut hormones were investigated after a meal. Investigations led to a dose escalation study with glucagon like peptide-2 (GLP-2) in postmenopausal women. We found a dose-dependent effect of GLP-2 on the reduction of bone resorption.",

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AU - Henriksen, Dennis B

AU - Alexandersen, Peter

AU - Bjarnason, Nina H

AU - Vilsbøll, Tina

AU - Hartmann, Bolette

AU - Henriksen, Eva E G

AU - Byrjalsen, Inger

AU - Krarup, Thure

AU - Holst, Jens Juul

AU - Christiansen, Claus

PY - 2003/12/1

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N2 - Collagen type I fragments, reflecting bone resorption, and release of gut hormones were investigated after a meal. Investigations led to a dose escalation study with glucagon like peptide-2 (GLP-2) in postmenopausal women. We found a dose-dependent effect of GLP-2 on the reduction of bone resorption.

AB - Collagen type I fragments, reflecting bone resorption, and release of gut hormones were investigated after a meal. Investigations led to a dose escalation study with glucagon like peptide-2 (GLP-2) in postmenopausal women. We found a dose-dependent effect of GLP-2 on the reduction of bone resorption.

U2 - http://dx.doi.org/10.1359/jbmr.2003.18.12.2180

DO - http://dx.doi.org/10.1359/jbmr.2003.18.12.2180

M3 - Journal article

SN - 0884-0431

VL - 18

SP - 2180

EP - 2190

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

IS - 12

ER -

Role of gastrointestinal hormones in postprandial reduction of bone resorption

Abstract

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