Abstract
INTRODUCTION: We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
METHODS: Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO2 -max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension.
RESULTS: VO2 -max and muscle strength were unchanged during run-in (-4.9% ± 10.3%, P = 0.80 and -3.7% ± 10.1%, P = 0.17, respectively). Aerobic exercise increased VO2 -max by 11.0% ± 14.7% (P = 0.02). Resistance exercise resulted in an increase of 13.8% ± 16.0% (P = 0.0004) in cIKS.
DISCUSSION: Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57: 70-76, 2018.
| Original language | English |
|---|---|
| Journal | Muscle & Nerve |
| Volume | 57 |
| Issue number | 1 |
| Pages (from-to) | 70-76 |
| ISSN | 0148-639X |
| DOIs | |
| Publication status | Published - Jan 2018 |
Keywords
- Anaerobic Threshold
- Bicycling
- Elbow/physiopathology
- Exercise
- Exercise Therapy/methods
- Female
- Humans
- Immunization, Passive
- Knee/physiopathology
- Male
- Middle Aged
- Muscle Strength
- Oxygen Consumption/physiology
- Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/physiopathology
- Quality of Life
- Resistance Training
- Treatment Outcome