TY - JOUR
T1 - Replicability and generalizability of PTSD networks
T2 - A cross-cultural multisite study of PTSD symptoms in four trauma patient samples
AU - Fried, Eiko I.
AU - Eidhof, Marloes B.
AU - Palic, Sabina
AU - Costantini, Giulio
AU - Huisman-van Dijk, Hilde M.
AU - Bockting, Claudi L. H.
AU - Engelhard, Iris
AU - Armour, Cherie
AU - Nielsen, Anni Brit Sternhagen
AU - Karstoft, Karen-Inge
PY - 2018
Y1 - 2018
N2 - The growing literature conceptualizing mental disorders like Posttraumatic Stress Disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise estimation, (b) non-clinical samples, and (c) single samples. This renders network structures in clinical data, and the extent to which networks replicate across datasets, unknown. To overcome these limitations, the present cross-cultural multisite study estimated regularized partial correlation networks of 16 PTSD symptoms across four datasets of traumatized patients receiving treatment for PTSD (total N=2,782). Despite differences in culture, trauma-type and severity of the samples, considerable similarities emerged, with moderate to high correlations between symptom profiles (0.43-0.82), network structures (0.62-0.74), and centrality estimates (0.63-0.75). We discuss the importance of future replicability efforts to improve clinical psychological science, and provide code, model output, and correlation matrices to make the results of this paper fully reproducible.
AB - The growing literature conceptualizing mental disorders like Posttraumatic Stress Disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise estimation, (b) non-clinical samples, and (c) single samples. This renders network structures in clinical data, and the extent to which networks replicate across datasets, unknown. To overcome these limitations, the present cross-cultural multisite study estimated regularized partial correlation networks of 16 PTSD symptoms across four datasets of traumatized patients receiving treatment for PTSD (total N=2,782). Despite differences in culture, trauma-type and severity of the samples, considerable similarities emerged, with moderate to high correlations between symptom profiles (0.43-0.82), network structures (0.62-0.74), and centrality estimates (0.63-0.75). We discuss the importance of future replicability efforts to improve clinical psychological science, and provide code, model output, and correlation matrices to make the results of this paper fully reproducible.
KW - Faculty of Health and Medical Sciences
KW - PTSD
KW - Screening
KW - Assessment
KW - Validation
KW - Military
KW - post-deployment mental health
KW - PTSD
KW - Networks
KW - Methodology
KW - Symptoms
KW - Cross-cultural
KW - Multisite study
U2 - 10.1177/2167702617745092
DO - 10.1177/2167702617745092
M3 - Journal article
C2 - 29881651
SN - 2167-7026
VL - 6
SP - 335
EP - 351
JO - Clinical Psychological Science
JF - Clinical Psychological Science
IS - 3
ER -