Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples

Eiko I. Fried; Marloes B. Eidhof; Sabina Palic; Giulio Costantini; Hilde M. Huisman-van Dijk; Claudi L. H. Bockting; Iris Engelhard; Cherie Armour; Anni Brit Sternhagen Nielsen; Karen-Inge Karstoft

doi:10.1177/2167702617745092

Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples

Eiko I. Fried, Marloes B. Eidhof, Sabina Palic, Giulio Costantini, Hilde M. Huisman-van Dijk, Claudi L. H. Bockting, Iris Engelhard, Cherie Armour, Anni Brit Sternhagen Nielsen, Karen-Inge Karstoft

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Abstract

The growing literature conceptualizing mental disorders like posttraumatic Stress Disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise network estimation, (b) non-clinical samples, and (c) single samples. This renders network structures in clinical data, and the extent to which networks replicate across datasets, unknown. To overcome these limitations, the present cross-cultural multisite study estimated regularized partial correlation networks of 16 PTSD symptoms across four datasets of traumatized patients receiving treatment for PTSD (total N=2,782), and compared resulting networks. Despite differences in culture, trauma-type and severity of the samples, considerable similarities emerged, with moderate to high correlations between symptom profiles (0.43 to 0.82), network
structures (0.62 to 0.74), and centrality estimates (0.63 to 0.75). We discuss the importance of future replicability efforts to improve clinical psychological science, and provide code, model output, and
correlation matrices to make the results of this paper fully reproducible.

Originalsprog	Engelsk
Tidsskrift	Clinical Psychological Science
Vol/bind	6
Udgave nummer	3
Sider (fra-til)	335-351
Antal sider	17
ISSN	2167-7026
DOI	https://doi.org/10.1177/2167702617745092
Status	Udgivet - 2018

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Det Sundhedsvidenskabelige Fakultet
PTSD
Screening
Assessment
Validation
Military
post-deployment mental health

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10.1177/2167702617745092Licens: CC BY-NC

Replicability and Generalizability of Posttraumatic Stress Disorder (PTSD) NetworksForlagets udgivne version, 530 KBLicens: CC BY-NC

Citationsformater

Fried, E. I., Eidhof, M. B., Palic, S., Costantini, G., Huisman-van Dijk, H. M., Bockting, C. L. H., Engelhard, I., Armour, C., Nielsen, A. B. S., & Karstoft, K.-I. (2018). Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples. Clinical Psychological Science, 6(3), 335-351. https://doi.org/10.1177/2167702617745092

Fried, EI, Eidhof, MB, Palic, S, Costantini, G, Huisman-van Dijk, HM, Bockting, CLH, Engelhard, I, Armour, C, Nielsen, ABS & Karstoft, K-I 2018, 'Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples', Clinical Psychological Science, bind 6, nr. 3, s. 335-351. https://doi.org/10.1177/2167702617745092

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title = "Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples",

abstract = "The growing literature conceptualizing mental disorders like Posttraumatic Stress Disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise estimation, (b) non-clinical samples, and (c) single samples. This renders network structures in clinical data, and the extent to which networks replicate across datasets, unknown. To overcome these limitations, the present cross-cultural multisite study estimated regularized partial correlation networks of 16 PTSD symptoms across four datasets of traumatized patients receiving treatment for PTSD (total N=2,782). Despite differences in culture, trauma-type and severity of the samples, considerable similarities emerged, with moderate to high correlations between symptom profiles (0.43-0.82), network structures (0.62-0.74), and centrality estimates (0.63-0.75). We discuss the importance of future replicability efforts to improve clinical psychological science, and provide code, model output, and correlation matrices to make the results of this paper fully reproducible.",

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author = "Fried, {Eiko I.} and Eidhof, {Marloes B.} and Sabina Palic and Giulio Costantini and {Huisman-van Dijk}, {Hilde M.} and Bockting, {Claudi L. H.} and Iris Engelhard and Cherie Armour and Nielsen, {Anni Brit Sternhagen} and Karen-Inge Karstoft",

year = "2018",

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AU - Costantini, Giulio

AU - Huisman-van Dijk, Hilde M.

AU - Bockting, Claudi L. H.

AU - Engelhard, Iris

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AU - Nielsen, Anni Brit Sternhagen

AU - Karstoft, Karen-Inge

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AB - The growing literature conceptualizing mental disorders like Posttraumatic Stress Disorder (PTSD) as networks of interacting symptoms faces three key challenges. Prior studies predominantly used (a) small samples with low power for precise estimation, (b) non-clinical samples, and (c) single samples. This renders network structures in clinical data, and the extent to which networks replicate across datasets, unknown. To overcome these limitations, the present cross-cultural multisite study estimated regularized partial correlation networks of 16 PTSD symptoms across four datasets of traumatized patients receiving treatment for PTSD (total N=2,782). Despite differences in culture, trauma-type and severity of the samples, considerable similarities emerged, with moderate to high correlations between symptom profiles (0.43-0.82), network structures (0.62-0.74), and centrality estimates (0.63-0.75). We discuss the importance of future replicability efforts to improve clinical psychological science, and provide code, model output, and correlation matrices to make the results of this paper fully reproducible.

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KW - PTSD

KW - Screening

KW - Assessment

KW - Validation

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KW - post-deployment mental health

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KW - Networks

KW - Methodology

KW - Symptoms

KW - Cross-cultural

KW - Multisite study

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DO - 10.1177/2167702617745092

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Replicability and generalizability of PTSD networks: A cross-cultural multisite study of PTSD symptoms in four trauma patient samples

Abstract

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