Abstract
Concern has been expressed as to the reliability of clinical ICD-10 diagnosis of schizophrenia. This study was designed to assess the diagnostic reliability of the clinical ICD-10 diagnosis of schizophrenia in a random sample of Danish in- and outpatients with a history of psychosis. A sample of 100 subjects was assessed using the operational criteria OPCRIT checklist for psychotic and affective illness. The most recent principal and clinical ICD-10 diagnosis was compared with diagnoses generated by the OPCRIT instrument. Data documented very high sensitivity (93%) and positive predictive value (87%) of ICD-10 schizophrenia and an overall good agreement between clinical and OPCRIT-derived diagnoses (kappa=0.60). An even higher positive predictive value was obtained when diagnoses were amalgamated into a diagnostic entity of schizophrenia-spectrum disorders (98%). Near perfect agreement was seen between OPCRIT-derived ICD-10 and DSM-IV diagnoses (kappa=0.87). Thus, this study demonstrates high reliability of the clinical diagnosis of schizophrenia and even more so of the diagnosis of schizophrenia-spectrum disorder.
| Original language | English |
|---|---|
| Journal | Nordic Journal of Psychiatry |
| Volume | 59 |
| Issue number | 3 |
| Pages (from-to) | 209-12 |
| Number of pages | 4 |
| ISSN | 0803-9488 |
| DOIs | |
| Publication status | Published - 2005 |
Keywords
- Adult
- Denmark
- Female
- Humans
- International Classification of Diseases
- Male
- Predictive Value of Tests
- Psychiatric Status Rating Scales
- Psychotic Disorders
- Reproducibility of Results
- Schizophrenia
- Schizophrenic Psychology
- Sensitivity and Specificity
- Comparative Study
- Journal Article
- Research Support, Non-U.S. Gov't