Abstract
The present study investigates, at farm level, the effect of the time-span between sampling and the last time a particular antimicrobial growth promoter (AGP) was included in the feed on the probability of selecting an AGP-resistant Enterococcus faecium isolate from a broiler flock. The probability that a randomly selected E. faecium isolate was resistant to avilamycin, erythromycin or virginiamycin was 0.91, 0.92 and 0.84, respectively if the isolate originated from a broiler flock fed either avilamycin- or virginiamycin-supplemented feed. As the time-span between sampling and the last AGP consumption increased, the probability of isolating an E. faecium isolate resistant to a particular AGP decreased (probability <0.2 within 3-5 years after last exposure to AGPs). The decrease in probability over time showed little farm-to-farm variation. The number of times a particular AGP was given to previous flocks reared in the same house had no effect on the probability of isolating a resistant isolate.
| Original language | English |
|---|---|
| Journal | Epidemiology and Infection |
| Volume | 132 |
| Issue number | 1 |
| Pages (from-to) | 95-105 |
| Number of pages | 11 |
| ISSN | 0950-2688 |
| Publication status | Published - Jan 2004 |
| Externally published | Yes |
Keywords
- Animal Feed
- Animal Husbandry
- Animals
- Anti-Bacterial Agents
- Chickens
- Denmark
- Drug Administration Schedule
- Drug Resistance, Bacterial
- Enterococcus faecium
- Erythromycin
- Gram-Positive Bacterial Infections
- Linear Models
- Logistic Models
- Markov Chains
- Microbial Sensitivity Tests
- Monte Carlo Method
- Oligosaccharides
- Poultry Diseases
- Time Factors
- Vancomycin
- Virginiamycin
- Journal Article