Relations between the consumption of antimicrobial growth promoters and the occurrence of resistance among Enterococcus faecium isolated from broilers

H D Emborg; J S Andersen; A M Seyfarth; Henrik Caspar Wegener

Relations between the consumption of antimicrobial growth promoters and the occurrence of resistance among Enterococcus faecium isolated from broilers

H D Emborg, J S Andersen, A M Seyfarth, Henrik Caspar Wegener

26 Citationer (Scopus)

Abstract

The present study investigates, at farm level, the effect of the time-span between sampling and the last time a particular antimicrobial growth promoter (AGP) was included in the feed on the probability of selecting an AGP-resistant Enterococcus faecium isolate from a broiler flock. The probability that a randomly selected E. faecium isolate was resistant to avilamycin, erythromycin or virginiamycin was 0.91, 0.92 and 0.84, respectively if the isolate originated from a broiler flock fed either avilamycin- or virginiamycin-supplemented feed. As the time-span between sampling and the last AGP consumption increased, the probability of isolating an E. faecium isolate resistant to a particular AGP decreased (probability <0.2 within 3-5 years after last exposure to AGPs). The decrease in probability over time showed little farm-to-farm variation. The number of times a particular AGP was given to previous flocks reared in the same house had no effect on the probability of isolating a resistant isolate.

Originalsprog	Engelsk
Tidsskrift	Epidemiology and Infection
Vol/bind	132
Udgave nummer	1
Sider (fra-til)	95-105
Antal sider	11
ISSN	0950-2688
Status	Udgivet - jan. 2004
Udgivet eksternt	Ja

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title = "Relations between the consumption of antimicrobial growth promoters and the occurrence of resistance among Enterococcus faecium isolated from broilers",

abstract = "The present study investigates, at farm level, the effect of the time-span between sampling and the last time a particular antimicrobial growth promoter (AGP) was included in the feed on the probability of selecting an AGP-resistant Enterococcus faecium isolate from a broiler flock. The probability that a randomly selected E. faecium isolate was resistant to avilamycin, erythromycin or virginiamycin was 0.91, 0.92 and 0.84, respectively if the isolate originated from a broiler flock fed either avilamycin- or virginiamycin-supplemented feed. As the time-span between sampling and the last AGP consumption increased, the probability of isolating an E. faecium isolate resistant to a particular AGP decreased (probability <0.2 within 3-5 years after last exposure to AGPs). The decrease in probability over time showed little farm-to-farm variation. The number of times a particular AGP was given to previous flocks reared in the same house had no effect on the probability of isolating a resistant isolate.",

keywords = "Animal Feed, Animal Husbandry, Animals, Anti-Bacterial Agents, Chickens, Denmark, Drug Administration Schedule, Drug Resistance, Bacterial, Enterococcus faecium, Erythromycin, Gram-Positive Bacterial Infections, Linear Models, Logistic Models, Markov Chains, Microbial Sensitivity Tests, Monte Carlo Method, Oligosaccharides, Poultry Diseases, Time Factors, Vancomycin, Virginiamycin, Journal Article",

author = "Emborg, {H D} and Andersen, {J S} and Seyfarth, {A M} and Wegener, {Henrik Caspar}",

year = "2004",

month = jan,

language = "English",

volume = "132",

pages = "95--105",

journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

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TY - JOUR

T1 - Relations between the consumption of antimicrobial growth promoters and the occurrence of resistance among Enterococcus faecium isolated from broilers

AU - Emborg, H D

AU - Andersen, J S

AU - Seyfarth, A M

AU - Wegener, Henrik Caspar

PY - 2004/1

Y1 - 2004/1

N2 - The present study investigates, at farm level, the effect of the time-span between sampling and the last time a particular antimicrobial growth promoter (AGP) was included in the feed on the probability of selecting an AGP-resistant Enterococcus faecium isolate from a broiler flock. The probability that a randomly selected E. faecium isolate was resistant to avilamycin, erythromycin or virginiamycin was 0.91, 0.92 and 0.84, respectively if the isolate originated from a broiler flock fed either avilamycin- or virginiamycin-supplemented feed. As the time-span between sampling and the last AGP consumption increased, the probability of isolating an E. faecium isolate resistant to a particular AGP decreased (probability <0.2 within 3-5 years after last exposure to AGPs). The decrease in probability over time showed little farm-to-farm variation. The number of times a particular AGP was given to previous flocks reared in the same house had no effect on the probability of isolating a resistant isolate.

AB - The present study investigates, at farm level, the effect of the time-span between sampling and the last time a particular antimicrobial growth promoter (AGP) was included in the feed on the probability of selecting an AGP-resistant Enterococcus faecium isolate from a broiler flock. The probability that a randomly selected E. faecium isolate was resistant to avilamycin, erythromycin or virginiamycin was 0.91, 0.92 and 0.84, respectively if the isolate originated from a broiler flock fed either avilamycin- or virginiamycin-supplemented feed. As the time-span between sampling and the last AGP consumption increased, the probability of isolating an E. faecium isolate resistant to a particular AGP decreased (probability <0.2 within 3-5 years after last exposure to AGPs). The decrease in probability over time showed little farm-to-farm variation. The number of times a particular AGP was given to previous flocks reared in the same house had no effect on the probability of isolating a resistant isolate.

KW - Animal Feed

KW - Animal Husbandry

KW - Animals

KW - Anti-Bacterial Agents

KW - Chickens

KW - Denmark

KW - Drug Administration Schedule

KW - Drug Resistance, Bacterial

KW - Enterococcus faecium

KW - Erythromycin

KW - Gram-Positive Bacterial Infections

KW - Linear Models

KW - Logistic Models

KW - Markov Chains

KW - Microbial Sensitivity Tests

KW - Monte Carlo Method

KW - Oligosaccharides

KW - Poultry Diseases

KW - Time Factors

KW - Vancomycin

KW - Virginiamycin

KW - Journal Article

M3 - Journal article

C2 - 14979595

SN - 0950-2688

VL - 132

SP - 95

EP - 105

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 1

ER -

Relations between the consumption of antimicrobial growth promoters and the occurrence of resistance among Enterococcus faecium isolated from broilers

Abstract

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