Radionuklidbehandling af neuroendokrine tumorer

Translated title of the contribution: [Radionuclide therapy for neuroendocrine tumours]

Jann Mortensen, Peter Oturai, Liselotte Højgaard, Ulrich Knigge, Carsten Palnaes Hansen, Lars Martiný, Palle Rasmussen, Andreas Kjær, Peter Sandor Oturai

    Abstract

    Peptide receptor radionuclide therapy using somatostatin analogues labelled with beta-emitting isotopes can be given to patients with metastasized or inoperable neuroendocrine tumours provided these have increased uptake on octreotide scintigraphy. This is a brief review of the treatment principle, indications and contraindications and practices with (177)Lu-DOTATATE treatment used at Rigshospitalet. Side effects are generally mild and reversible. Severe long-term side effects are rare. The majority of patients will experience increased quality of life and partial tumour reduction or stabilization for a period of time. However, up to 20% will experience no treatment effect.
    Translated title of the contribution[Radionuclide therapy for neuroendocrine tumours]
    Original languageDanish
    JournalUgeskrift for Laeger
    Volume172
    Issue number43
    Pages (from-to)2950-3
    Number of pages4
    ISSN0041-5782
    Publication statusPublished - 25 Oct 2010

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