Radionuklidbehandling af neuroendokrine tumorer

Jann Mortensen, Peter Oturai, Liselotte Højgaard, Ulrich Knigge, Carsten Palnaes Hansen, Lars Martiný, Palle Rasmussen, Andreas Kjær, Peter Sandor Oturai

    Abstract

    Peptide receptor radionuclide therapy using somatostatin analogues labelled with beta-emitting isotopes can be given to patients with metastasized or inoperable neuroendocrine tumours provided these have increased uptake on octreotide scintigraphy. This is a brief review of the treatment principle, indications and contraindications and practices with (177)Lu-DOTATATE treatment used at Rigshospitalet. Side effects are generally mild and reversible. Severe long-term side effects are rare. The majority of patients will experience increased quality of life and partial tumour reduction or stabilization for a period of time. However, up to 20% will experience no treatment effect.
    Bidragets oversatte titel[Radionuclide therapy for neuroendocrine tumours]
    OriginalsprogDansk
    TidsskriftUgeskrift for Laeger
    Vol/bind172
    Udgave nummer43
    Sider (fra-til)2950-3
    Antal sider4
    ISSN0041-5782
    StatusUdgivet - 25 okt. 2010

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