Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues

Gopal Raghunath Karemore; Sujatha N. Raja; Lavanya Rai; V.B Kartha; Santhosh C

doi:10.1117/12.809972

Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues

Gopal Raghunath Karemore, Sujatha N. Raja, Lavanya Rai, V.B Kartha, Santhosh C

Department of Computer Science

Abstract

Protein profiles of tissue homogenates were recorded using HPLC separation and LIF detection method. The samples were collected from volunteers with clinically normal or cervical cancer conditions. It is shown that the protein profile can be classified as belonging to malignant or normal state by using hard and Fuzzy clustering methods. The study was performed to test the utility of the HPLC-LIF protein profiling method for classification of tissue samples as well as to establish a complementary method for histopathology for clinical diagnosis of the tissue as normal or malignant.

Original language	English
Title of host publication	Proceedings of the SPIE
Number of pages	8
Volume	7169
Publication date	2009
DOIs	https://doi.org/10.1117/12.809972
Publication status	Published - 2009
Event	Advanced Biomedical and Clinical Diagnostic Systems VII - California, United States Duration: 25 Jan 2009 → 26 Jan 2009

Conference

Conference	Advanced Biomedical and Clinical Diagnostic Systems VII
Country/Territory	United States
City	California
Period	25/01/2009 → 26/01/2009

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10.1117/12.809972

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Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues. / Karemore, Gopal Raghunath; Raja, Sujatha N.; Rai, Lavanya et al.
Proceedings of the SPIE. Vol. 7169 2009.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Karemore, GR, Raja, SN, Rai, L, Kartha, VB & C, S 2009, Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues. in Proceedings of the SPIE. vol. 7169, Advanced Biomedical and Clinical Diagnostic Systems VII, California, United States, 25/01/2009. https://doi.org/10.1117/12.809972

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abstract = " Protein profiles of tissue homogenates were recorded using HPLC separation and LIF detection method. The samples were collected from volunteers with clinically normal or cervical cancer conditions. It is shown that the protein profile can be classified as belonging to malignant or normal state by using hard and Fuzzy clustering methods. The study was performed to test the utility of the HPLC-LIF protein profiling method for classification of tissue samples as well as to establish a complementary method for histopathology for clinical diagnosis of the tissue as normal or malignant. ",

author = "Karemore, {Gopal Raghunath} and Raja, {Sujatha N.} and Lavanya Rai and V.B Kartha and Santhosh C",

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M3 - Article in proceedings

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BT - Proceedings of the SPIE

Y2 - 25 January 2009 through 26 January 2009

ER -

Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues

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