Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method: Case of malignant and normal cervical tissues

TY - GEN

T1 - Protein Profile study of clinical samples using Laser Induced Fluorescence as the detection method

T2 -  <strong>Advanced Biomedical and Clinical Diagnostic Systems VII</strong>

AU - Karemore, Gopal Raghunath

AU - Raja, Sujatha N.

AU - Rai, Lavanya

AU - Kartha, V.B

AU - C, Santhosh

PY - 2009

Y1 - 2009

N2 -   Protein profiles of tissue homogenates were recorded using HPLC separation and LIF detection method. The samples were collected from volunteers with clinically normal or cervical cancer conditions. It is shown that the protein profile can be classified as belonging to malignant or normal state by using hard and Fuzzy clustering methods. The study was performed to test the utility of the HPLC-LIF protein profiling method for classification of tissue samples as well as to establish a complementary method for histopathology for clinical diagnosis of the tissue as normal or malignant.  

AB -   Protein profiles of tissue homogenates were recorded using HPLC separation and LIF detection method. The samples were collected from volunteers with clinically normal or cervical cancer conditions. It is shown that the protein profile can be classified as belonging to malignant or normal state by using hard and Fuzzy clustering methods. The study was performed to test the utility of the HPLC-LIF protein profiling method for classification of tissue samples as well as to establish a complementary method for histopathology for clinical diagnosis of the tissue as normal or malignant.  

U2 - 10.1117/12.809972

DO - 10.1117/12.809972

M3 - Article in proceedings

VL - 7169

BT - Proceedings of the SPIE

Y2 - 25 January 2009 through 26 January 2009

ER -