Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation

Keyphrases

• C Protein 100%
• Dominant Negative 11%
• Expression Level 11%
• Jurkat 11%
• Knock-in Mouse Model 11%
• Knockdown 11%
• Leucine 11%
• Mouse T Cells 11%
• Negative Type 11%
• PKCbeta 44%
• Primary T Cells 11%
• Protein Kinase 100%
• Protein Kinase C theta (PKCθ) 100%
• Receptor Sorting 11%
• Recycling Pathway 11%
• RNA-based 11%
• Small Interfering RNA (siRNA) 11%
• Sorting Motif 11%
• Specificity Protein 1 11%
• Surface Expression 11%
• T Cell Lines 22%
• T Cells 22%
• α-kinase 100%

Immunology and Microbiology

• Cell Line 16%
• Cell Surface 8%
• Downregulation 100%
• Isotype 100%
• Knockout Mouse 8%
• Leucine 8%
• Protein Kinase C 100%
• T Cell 33%
• T Cell Receptor 100%

Neuroscience

• calcium activated,phospholipid dependent protein kinase 100%
• Cell Line 25%
• Leucine 12%
• Protein 12%
• Protein Kinase C Alpha 100%
• Protein Kinase C Theta 100%
• Receptor 12%
• Small Interfering RNA 12%
• T Cell 50%