Research output per year
Research output per year
Personal profile
Primary fields of research
http://isim.ku.dk/research/t_cell_biology/
Current research
http://isim.ku.dk/research/t_cell_biology/
CV
Born August 2, 1956.
Education and Academic Degrees
- 1982 Medical doctor (MD), University of Copenhagen (UC), Denmark.
- 1994 PhD in immunology, UC.
- 1995 DMSc in medicine/immunology, UC.
Employment and Positions
- 1982 - 1987 Resident and senior resident at medical, surgical and clinical immunological wards at University Hospitals in Copenhagen.
- 1987 - 1990 Research scholar supported by the Danish Medical Research Council and by the Academy of Science.
- 1990 - 1992 Senior research fellow supported by the Danish Cancer Society.
- 1992 - 2005 Associate professor in molecular immunology, UC.
- 2005 - Full professor in molecular immunology, UC.
Honorary Offices and Administration
- 1999 - 2005 Member of the Scientific Committee of the Faculty of Health Sciences.
- 2000 - 2006 Member/Chairman of the board of The Weimann Foundation.
- 2002 - 2006 Head of the Department of Medical Microbiology and Immunology.
- 2006 - 2010 Research leader for Copenhagen Cluster of Immunology.
- 2007 - Head/Chairman of the Department of International Health, Immunology and Microbiology.
Referee
Referee at Cell, EMBO Journal, Journal of Immunology, PloSONE, Critical Reviews in Immunology, Blood, Scandinavian Journal of Immunology, International Immunology, Molecular Immunology, Journal of Oral Pathology and Medicine and APMIS.
Research interests
The immune system with focus on T cells. Structure and function of the T cell receptor. T cell receptor signalling. T cell development and activation. T cells and inflammation.
Author or co-author on more than 100 papers listed in PubMed
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Health and Medical Sciences
- Immunology
- T cell biology
- T cell receptor
- Immune regulation
- Inflammation
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Vitamin D controls T cell antigen receptor signaling and activation of human T cells
von Essen, M. R., Kongsbak-Wismann, M., Schjerling, P., Ølgaard, K., Ødum, N. & Geisler, C., 2010, In: Nature Immunology. 11, 4, p. 344-349 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TCR down-regulation controls T cell homeostasis
Boding, L., Bonefeld, C. M., Nielsen, B. L., Lauritsen, J. P. H., von Essen, M. R., Hansen, A. K., Larsen, J. M., Nielsen, M. M., Odum, N. & Geisler, C., 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation
von Essen, M., Nielsen, M. W., Bonefeld, C. M., Boding, L., Larsen, J. M., Leitges, M., Baier, G., Odum, N. & Geisler, C., 2006, In: Journal of Immunology. 176, 12, p. 7502-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
50 Citations (Scopus) -
Constitutive and ligand-induced TCR degradation
von Essen, M., Bonefeld, C. M., Siersma, V., Rasmussen, A. B., Lauritsen, J. P. H., Nielsen, B. L. & Geisler, C., 2004, In: Journal of Immunology. 173, 1, p. 384-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
39 Citations (Scopus) -
TCR trafficking in resting and stimulated T cells
Geisler, C., 2004, In: Critical Reviews in Immunology. 24, 1, p. 67-86 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
69 Citations (Scopus) -
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism
Bonefeld, C. M., Rasmussen, B. A., Lauritsen, J. P., von Essen, M., Odum, N., Andersen, P. S. & Geisler, C., 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling
Menné, C., Møller Sørensen, T., Siersma, V., von Essen, M., Ødum, N. & Geisler, C., 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
36 Citations (Scopus) -
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling
Dietrich, J., Menné, C., Lauritsen, J. P. H., von Essen, M., Rasmussen, B. A., Ødum, N. & Geisler, C., 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
39 Citations (Scopus)